Long-Term Treatment with Cannabidiol-Enriched <i>Cannabis</i> Extract Induces Synaptic Changes in the Adolescent Rat Hippocampus

Long-Term Treatment with Cannabidiol-Enriched <i>Cannabis</i> Extract Induces Synaptic Changes in the Adolescent Rat Hippocampus

The endocannabinoid system (eCS) is widely distributed in mammalian tissues and it is classically formed by cannabinoid receptors, endogenous bioactive lipids and its synthesis and degradation enzymes. Due to the modulatory role of eCS in synaptic activity in the Central Nervous System (CNS), phytoc...

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Bibliographic Details
Main Authors: Andrey F. L. Aguiar, Raquel M. P. Campos, Alinny R. Isaac, Yolanda Paes-Colli, Virgínia M. Carvalho, Luzia S. Sampaio, Ricardo A. de Melo Reis
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:International Journal of Molecular Sciences
Subjects:
<i>Cannabis</i>
endocannabinoid system
synaptic changes
Online Access:https://www.mdpi.com/1422-0067/24/14/11775

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