A clinical study of using a phentolamine alcohol wet dressing in the treatment of extravasation after a 20% fat emulsion intravenous infusion - a randomised trial
Introduction/Objective. The aim of our paper was to investigate the clinical efficacy of using a phentolamine alcohol wet dressing to treat the extravasation of an intravenously administered infusion of milk fat. This study was designed as a randomized trial, and was done at the Hengshui people’s Ho...
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| Format: | Article |
| Language: | English |
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Serbian Medical Society
2022-01-01
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| Series: | Srpski Arhiv za Celokupno Lekarstvo |
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| Online Access: | http://www.doiserbia.nb.rs/img/doi/0370-8179/2022/0370-81792200088Y.pdf |
| _version_ | 1811178347873435648 |
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| author | Yuan-Wei Fu Zhen-Yuan Liu |
| author_facet | Yuan-Wei Fu Zhen-Yuan Liu |
| author_sort | Yuan-Wei Fu |
| collection | DOAJ |
| description | Introduction/Objective. The aim of our paper was to investigate the clinical efficacy of using a phentolamine alcohol wet dressing to treat the extravasation of an intravenously administered infusion of milk fat. This study was designed as a randomized trial, and was done at the Hengshui people’s Hospital, Hebei Province, China, from June 2019 to June 2020. Methods. In total, 300 patients were randomly divided into two groups. In the experimental group, the patients were treated using a phentolamine alcohol wet dressing, whereas in the control group, the patients were treated using a hydropathic compress with a 50% magnesium sulphate solution. The cure rate, healing time, and patient satisfaction of the two groups were compared and analyzed. Results. The cure rate of intravenous infusion extravasation was 92.67% (139/150) in the experimental group and 70.67% (106/150) in the control group (p < 0.05). In the experimental group, there were 66 patients whose cure time was less than 24 hours, 62 patients whose cure time was between 24 and 48 hours, and 22 patients whose cure time was over 48 hours. The cure time of the patients was significantly shorter in the experimental group than the control group. After treatment, in the experimental group, 67 patients were very satisfied, 52 patients were satisfied, 21 patients were generally satisfied, and 10 patients were dissatisfied; in the control group, 32 patients were very satisfied, 40 patients were satisfied, 56 patients were generally satisfied, and 22 patients were dissatisfied. The satisfaction of patients was significantly higher in the experimental group than in the control group. Conclusion. The effect of using a phentolamine alcohol wet dressing to treat the extravasation of an intravenous infusion of milk fat is significantly better than the effect of using a magnesium sulphate solution, and this type of dressing is worthy of clinical application. |
| first_indexed | 2024-04-11T06:16:47Z |
| format | Article |
| id | doaj.art-d3c471e14e79479ea5dc4e9582ec5c15 |
| institution | Directory Open Access Journal |
| issn | 0370-8179 2406-0895 |
| language | English |
| last_indexed | 2024-04-11T06:16:47Z |
| publishDate | 2022-01-01 |
| publisher | Serbian Medical Society |
| record_format | Article |
| series | Srpski Arhiv za Celokupno Lekarstvo |
| spelling | doaj.art-d3c471e14e79479ea5dc4e9582ec5c152022-12-22T04:41:02ZengSerbian Medical SocietySrpski Arhiv za Celokupno Lekarstvo0370-81792406-08952022-01-011509-1053954310.2298/SARH210604088Y0370-81792200088YA clinical study of using a phentolamine alcohol wet dressing in the treatment of extravasation after a 20% fat emulsion intravenous infusion - a randomised trialYuan-Wei Fu0Zhen-Yuan Liu1Hengshui people's Hospital, The First Department of rehabilitation medicine, Hebei Province, ChinaHengshui people's Hospital, The First Department of rehabilitation medicine, Hebei Province, ChinaIntroduction/Objective. The aim of our paper was to investigate the clinical efficacy of using a phentolamine alcohol wet dressing to treat the extravasation of an intravenously administered infusion of milk fat. This study was designed as a randomized trial, and was done at the Hengshui people’s Hospital, Hebei Province, China, from June 2019 to June 2020. Methods. In total, 300 patients were randomly divided into two groups. In the experimental group, the patients were treated using a phentolamine alcohol wet dressing, whereas in the control group, the patients were treated using a hydropathic compress with a 50% magnesium sulphate solution. The cure rate, healing time, and patient satisfaction of the two groups were compared and analyzed. Results. The cure rate of intravenous infusion extravasation was 92.67% (139/150) in the experimental group and 70.67% (106/150) in the control group (p < 0.05). In the experimental group, there were 66 patients whose cure time was less than 24 hours, 62 patients whose cure time was between 24 and 48 hours, and 22 patients whose cure time was over 48 hours. The cure time of the patients was significantly shorter in the experimental group than the control group. After treatment, in the experimental group, 67 patients were very satisfied, 52 patients were satisfied, 21 patients were generally satisfied, and 10 patients were dissatisfied; in the control group, 32 patients were very satisfied, 40 patients were satisfied, 56 patients were generally satisfied, and 22 patients were dissatisfied. The satisfaction of patients was significantly higher in the experimental group than in the control group. Conclusion. The effect of using a phentolamine alcohol wet dressing to treat the extravasation of an intravenous infusion of milk fat is significantly better than the effect of using a magnesium sulphate solution, and this type of dressing is worthy of clinical application.http://www.doiserbia.nb.rs/img/doi/0370-8179/2022/0370-81792200088Y.pdfphentolamine alcohol wet dressingmagnesium sulphate solutionfat emulsion extravasationcure ratepatient satisfaction |
| spellingShingle | Yuan-Wei Fu Zhen-Yuan Liu A clinical study of using a phentolamine alcohol wet dressing in the treatment of extravasation after a 20% fat emulsion intravenous infusion - a randomised trial Srpski Arhiv za Celokupno Lekarstvo phentolamine alcohol wet dressing magnesium sulphate solution fat emulsion extravasation cure rate patient satisfaction |
| title | A clinical study of using a phentolamine alcohol wet dressing in the treatment of extravasation after a 20% fat emulsion intravenous infusion - a randomised trial |
| title_full | A clinical study of using a phentolamine alcohol wet dressing in the treatment of extravasation after a 20% fat emulsion intravenous infusion - a randomised trial |
| title_fullStr | A clinical study of using a phentolamine alcohol wet dressing in the treatment of extravasation after a 20% fat emulsion intravenous infusion - a randomised trial |
| title_full_unstemmed | A clinical study of using a phentolamine alcohol wet dressing in the treatment of extravasation after a 20% fat emulsion intravenous infusion - a randomised trial |
| title_short | A clinical study of using a phentolamine alcohol wet dressing in the treatment of extravasation after a 20% fat emulsion intravenous infusion - a randomised trial |
| title_sort | clinical study of using a phentolamine alcohol wet dressing in the treatment of extravasation after a 20 fat emulsion intravenous infusion a randomised trial |
| topic | phentolamine alcohol wet dressing magnesium sulphate solution fat emulsion extravasation cure rate patient satisfaction |
| url | http://www.doiserbia.nb.rs/img/doi/0370-8179/2022/0370-81792200088Y.pdf |
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