Toxoplasma gondii infection in children after allogeneic hematopoietic stem cell transplantation: A case report and literature review
ABSTRACT Introduction Toxoplasmosis is a life‐threatening complication after hematopoietic stem cell transplantation (HSCT). However, for several reasons, clinicians know little about Toxoplasma infection. Case presentation We report a case of toxoplasmosis that was diagnosed by bone marrow smear an...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2021-09-01
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| Series: | Pediatric Investigation |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/ped4.12290 |
| _version_ | 1818361530727530496 |
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| author | Lijuan Luo Nan Shen Wenjuan Chen Chengjuan Luo Xiaohang Huang Yuelian Jiang Qing Cao |
| author_facet | Lijuan Luo Nan Shen Wenjuan Chen Chengjuan Luo Xiaohang Huang Yuelian Jiang Qing Cao |
| author_sort | Lijuan Luo |
| collection | DOAJ |
| description | ABSTRACT Introduction Toxoplasmosis is a life‐threatening complication after hematopoietic stem cell transplantation (HSCT). However, for several reasons, clinicians know little about Toxoplasma infection. Case presentation We report a case of toxoplasmosis that was diagnosed by bone marrow smear and metagenomic next‐generation sequencing (mNGS) after HSCT in a boy. Additionally, we summarize the characteristics of toxoplasmosis after pediatric HSCT reported in the literature published in PubMed. Conclusion Clinicians should increase their awareness of toxoplasmosis in children after HSCT and implement pre‐transplant screening and post‐transplant monitoring and prevention in future according to the national conditions of our country. |
| first_indexed | 2024-12-13T21:18:09Z |
| format | Article |
| id | doaj.art-d3c86e8c6a1d4048b5eb261c84a8e271 |
| institution | Directory Open Access Journal |
| issn | 2574-2272 |
| language | English |
| last_indexed | 2024-12-13T21:18:09Z |
| publishDate | 2021-09-01 |
| publisher | Wiley |
| record_format | Article |
| series | Pediatric Investigation |
| spelling | doaj.art-d3c86e8c6a1d4048b5eb261c84a8e2712022-12-21T23:31:11ZengWileyPediatric Investigation2574-22722021-09-015323924310.1002/ped4.12290Toxoplasma gondii infection in children after allogeneic hematopoietic stem cell transplantation: A case report and literature reviewLijuan Luo0Nan Shen1Wenjuan Chen2Chengjuan Luo3Xiaohang Huang4Yuelian Jiang5Qing Cao6Department of Infectious Diseases Shanghai Children’s Medical Center School of Medicine Shanghai Jiao Tong University Shanghai ChinaDepartment of Infectious Diseases Shanghai Children’s Medical Center School of Medicine Shanghai Jiao Tong University Shanghai ChinaDepartment of Infectious Diseases Shanghai Children’s Medical Center School of Medicine Shanghai Jiao Tong University Shanghai ChinaDepartment of Hematology and Oncology Shanghai Children’s Medical Center School of Medicine Shanghai Jiao Tong University Shanghai ChinaDepartment of Hematology and Oncology Shanghai Children’s Medical Center School of Medicine Shanghai Jiao Tong University Shanghai ChinaDepartment of Pharmacy Shanghai Children’s Medical Center School of Medicine Shanghai Jiao Tong University Shanghai ChinaDepartment of Infectious Diseases Shanghai Children’s Medical Center School of Medicine Shanghai Jiao Tong University Shanghai ChinaABSTRACT Introduction Toxoplasmosis is a life‐threatening complication after hematopoietic stem cell transplantation (HSCT). However, for several reasons, clinicians know little about Toxoplasma infection. Case presentation We report a case of toxoplasmosis that was diagnosed by bone marrow smear and metagenomic next‐generation sequencing (mNGS) after HSCT in a boy. Additionally, we summarize the characteristics of toxoplasmosis after pediatric HSCT reported in the literature published in PubMed. Conclusion Clinicians should increase their awareness of toxoplasmosis in children after HSCT and implement pre‐transplant screening and post‐transplant monitoring and prevention in future according to the national conditions of our country.https://doi.org/10.1002/ped4.12290ToxoplasmosisHematopoietic stem cell transplantationPediatric |
| spellingShingle | Lijuan Luo Nan Shen Wenjuan Chen Chengjuan Luo Xiaohang Huang Yuelian Jiang Qing Cao Toxoplasma gondii infection in children after allogeneic hematopoietic stem cell transplantation: A case report and literature review Pediatric Investigation Toxoplasmosis Hematopoietic stem cell transplantation Pediatric |
| title | Toxoplasma gondii infection in children after allogeneic hematopoietic stem cell transplantation: A case report and literature review |
| title_full | Toxoplasma gondii infection in children after allogeneic hematopoietic stem cell transplantation: A case report and literature review |
| title_fullStr | Toxoplasma gondii infection in children after allogeneic hematopoietic stem cell transplantation: A case report and literature review |
| title_full_unstemmed | Toxoplasma gondii infection in children after allogeneic hematopoietic stem cell transplantation: A case report and literature review |
| title_short | Toxoplasma gondii infection in children after allogeneic hematopoietic stem cell transplantation: A case report and literature review |
| title_sort | toxoplasma gondii infection in children after allogeneic hematopoietic stem cell transplantation a case report and literature review |
| topic | Toxoplasmosis Hematopoietic stem cell transplantation Pediatric |
| url | https://doi.org/10.1002/ped4.12290 |
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