Outer Membrane Vesicles Protect Gram-Negative Bacteria against Host Defense Peptides

Antibiotic resistance is a pressing problem and estimated to be a leading cause of mortality by 2050. Antimicrobial peptides, also known as host defense peptides (HDPs), and HDP-derived antimicrobials have potent antimicrobial activity and high potential as alternatives to antibiotics due to low res...

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Dades bibliogràfiques
Autors principals: Melanie D. Balhuizen, Albert van Dijk, Jeroen W. A. Jansen, Chris H. A. van de Lest, Edwin J. A. Veldhuizen, Henk P. Haagsman
Format: Article
Idioma:English
Publicat: American Society for Microbiology 2021-08-01
Col·lecció:mSphere
Accés en línia:https://journals.asm.org/doi/10.1128/mSphere.00523-21
Descripció
Sumari:Antibiotic resistance is a pressing problem and estimated to be a leading cause of mortality by 2050. Antimicrobial peptides, also known as host defense peptides (HDPs), and HDP-derived antimicrobials have potent antimicrobial activity and high potential as alternatives to antibiotics due to low resistance development.
ISSN:2379-5042