Radiological Significance of Shear-Wave Elastography Technique for Evaluation of Solid Breast Masses with Histopathological Correlation
Background: Although various imaging modalities are available for evaluating suspicious breast lesions, ultrasound-based Shear-Wave Elastography (SWE) is an advanced, non-invasive technique complementary to grayscale sonography. This technique evaluates the elasticity of a specific tissue by applyi...
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| Format: | Article |
| Language: | English |
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University of Baghdad/ Al-Kindy College of Medicine
2023-12-01
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| Series: | مجله كليه طب الكندي |
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| Online Access: | https://jkmc.uobaghdad.edu.iq/index.php/MEDICAL/article/view/1218 |
| _version_ | 1797367569701666816 |
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| author | Niranjan Sahu Ashish Kumar Agrahari Bikash Parida Somadatta Das |
| author_facet | Niranjan Sahu Ashish Kumar Agrahari Bikash Parida Somadatta Das |
| author_sort | Niranjan Sahu |
| collection | DOAJ |
| description |
Background: Although various imaging modalities are available for evaluating suspicious breast lesions, ultrasound-based Shear-Wave Elastography (SWE) is an advanced, non-invasive technique complementary to grayscale sonography. This technique evaluates the elasticity of a specific tissue by applying sonic pressure to that tissue.
Objective: The aim is to assess the role of SWE in evaluating solid breast masses in correlation to histopathological study results.
Subjects and Methods: This prospective study was done in a tertiary care teaching hospital from September 2019 to August 2020. A study population of 50 women aged 18 years or above with an ultrasonographic (USG) diagnosis of solid breast masses was included.
Results: A significantly higher value of SWE elasticity ratio (E-mean) was observed in malignant tumors than in benign tumors (p <0.0001). The area-under-curve (AUC) for the BI-RADS 4 lesions was 0.522 (95% CI, 0.343-0.701) with an E-ratio cut-off score of 85.25, the sensitivity and specificity were 50% for diagnosing malignant tumors, whereas AUC for the HPE study was 1.000 (95% CI, 1.000-1.000) with an E-ratio cut-off score of 134.25; both the sensitivity and specificity were 100% for diagnosing malignant tumors.
Conclusions: Carcinoma breast is one of the most prevalent cancers globally. The most common benign tumor of the breast is a fibroadenoma, whereas Invasive Ductal Carcinoma is the most common malignant breast mass. A well-defined SWE elasticity ratio range might help predict the aggressiveness of breast tumors. SWE's correlation with BI-RADS in suspicious lesions adds to histopathology's advantage in distinguishing malignant tumors from benign ones.
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| first_indexed | 2024-03-08T17:19:15Z |
| format | Article |
| id | doaj.art-d3ce5fcfcb7341ffa1e88c5398b7b4be |
| institution | Directory Open Access Journal |
| issn | 1810-9543 2521-4365 |
| language | English |
| last_indexed | 2024-03-08T17:19:15Z |
| publishDate | 2023-12-01 |
| publisher | University of Baghdad/ Al-Kindy College of Medicine |
| record_format | Article |
| series | مجله كليه طب الكندي |
| spelling | doaj.art-d3ce5fcfcb7341ffa1e88c5398b7b4be2024-01-03T09:07:32ZengUniversity of Baghdad/ Al-Kindy College of Medicineمجله كليه طب الكندي1810-95432521-43652023-12-0119310.47723/kcmj.v19i3.12181144Radiological Significance of Shear-Wave Elastography Technique for Evaluation of Solid Breast Masses with Histopathological CorrelationNiranjan Sahu0Ashish Kumar Agrahari1Bikash Parida2Somadatta Das3Department of Radiodiagnosis, Institute of Medical Sciences and SUM Hospital, Siksha O Anusandhan Deemed to be University, Bhubaneswar-751003, Odisha, IndiaDepartment of Radiodiagnosis, Institute of Medical Sciences and Sum Hospital, Siksha ‘O’ Anusandhan Deemed to be University, Odisha, IndiaDepartment of Radiodiagnosis, Institute of Medical Sciences and Sum Hospital, Siksha ‘O’ Anusandhan Deemed to be University, Odisha, IndiaDepartment of Radiodiagnosis, Institute of Medical Sciences and Sum Hospital, Siksha ‘O’ Anusandhan Deemed to be University, Odisha, India Background: Although various imaging modalities are available for evaluating suspicious breast lesions, ultrasound-based Shear-Wave Elastography (SWE) is an advanced, non-invasive technique complementary to grayscale sonography. This technique evaluates the elasticity of a specific tissue by applying sonic pressure to that tissue. Objective: The aim is to assess the role of SWE in evaluating solid breast masses in correlation to histopathological study results. Subjects and Methods: This prospective study was done in a tertiary care teaching hospital from September 2019 to August 2020. A study population of 50 women aged 18 years or above with an ultrasonographic (USG) diagnosis of solid breast masses was included. Results: A significantly higher value of SWE elasticity ratio (E-mean) was observed in malignant tumors than in benign tumors (p <0.0001). The area-under-curve (AUC) for the BI-RADS 4 lesions was 0.522 (95% CI, 0.343-0.701) with an E-ratio cut-off score of 85.25, the sensitivity and specificity were 50% for diagnosing malignant tumors, whereas AUC for the HPE study was 1.000 (95% CI, 1.000-1.000) with an E-ratio cut-off score of 134.25; both the sensitivity and specificity were 100% for diagnosing malignant tumors. Conclusions: Carcinoma breast is one of the most prevalent cancers globally. The most common benign tumor of the breast is a fibroadenoma, whereas Invasive Ductal Carcinoma is the most common malignant breast mass. A well-defined SWE elasticity ratio range might help predict the aggressiveness of breast tumors. SWE's correlation with BI-RADS in suspicious lesions adds to histopathology's advantage in distinguishing malignant tumors from benign ones. https://jkmc.uobaghdad.edu.iq/index.php/MEDICAL/article/view/1218elastographyhistopathological correlationbreast masses |
| spellingShingle | Niranjan Sahu Ashish Kumar Agrahari Bikash Parida Somadatta Das Radiological Significance of Shear-Wave Elastography Technique for Evaluation of Solid Breast Masses with Histopathological Correlation مجله كليه طب الكندي elastography histopathological correlation breast masses |
| title | Radiological Significance of Shear-Wave Elastography Technique for Evaluation of Solid Breast Masses with Histopathological Correlation |
| title_full | Radiological Significance of Shear-Wave Elastography Technique for Evaluation of Solid Breast Masses with Histopathological Correlation |
| title_fullStr | Radiological Significance of Shear-Wave Elastography Technique for Evaluation of Solid Breast Masses with Histopathological Correlation |
| title_full_unstemmed | Radiological Significance of Shear-Wave Elastography Technique for Evaluation of Solid Breast Masses with Histopathological Correlation |
| title_short | Radiological Significance of Shear-Wave Elastography Technique for Evaluation of Solid Breast Masses with Histopathological Correlation |
| title_sort | radiological significance of shear wave elastography technique for evaluation of solid breast masses with histopathological correlation |
| topic | elastography histopathological correlation breast masses |
| url | https://jkmc.uobaghdad.edu.iq/index.php/MEDICAL/article/view/1218 |
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