Profiling estrogen, progesterone, and androgen receptors in colorectal cancer in relation to gender, menopausal status, clinical stage, and tumour sidedness

Profiling estrogen, progesterone, and androgen receptors in colorectal cancer in relation to gender, menopausal status, clinical stage, and tumour sidedness

BackgroundAlthough estrogen (ERα/ERβ), progesterone (PGR), and androgen (AR) receptors are pathologically altered in colorectal cancer (CRC), their simultaneous expression within the same cohort of patients was not previously measured.MethodsERα/ERβ/PGR/AR proteins were measured in archived paired n...

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Bibliographic Details
Main Authors: Bassem Refaat, Akhmed Aslam, Shakir Idris, Ahmed H. Almalki, Mofareh Y. Alkhaldi, Hassan A. Asiri, Riyad A. Almaimani, Abdulrahman Mujalli, Faisal Minshawi, Sara A. Alamri, Mona I. AlHussain, Badee A. Baltow, Mansour H. Alqasmi, Ghaiyda T. Basfar, Ohoud M. Alosaimi, Ibrahim A. Muhayya
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Endocrinology
Subjects:
testosterone
cell cycle
apoptosis
left-right dichotomy
mifepristone
bicalutamide
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1187259/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2023.1187259/full

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