UL49 is an essential subunit of the viral pre-initiation complex that regulates human cytomegalovirus gene transcription

UL49 is an essential subunit of the viral pre-initiation complex that regulates human cytomegalovirus gene transcription

Summary: More than half the world’s population is infected with human cytomegalovirus (HCMV), causing congenital birth defects and impacting the immuno-compromised. Many of the >170 HCMV genes remain uncharacterized, and this gap in knowledge limits the development of novel antivirals. In this st...

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Bibliographic Details
Main Authors: Declan L. Turner, Svenja Fritzlar, Sara Sadeghipour, Adele A. Barugahare, Brendan E. Russ, Stephen J. Turner, Rommel A. Mathias
Format: Article
Language:English
Published: Elsevier 2022-10-01
Series:iScience
Subjects:
Molecular biology
virology
transcriptomics
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222014407

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