Cirurgia de intenção curativa nos tumores peri-ampulares. Resultados de 48 ressecções consecutivas.
Periampullary tumors form a clinical entity with common symptoms, similar therapeutic options, unsatisfactory resectability rates and unfavorable prognosis. From April 1970 until March 1994, one hundred and twenty-seven patients with periampullary carcinoma were operated by our surgical team. In 48...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Ordem dos Médicos
1995-12-01
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| Series: | Acta Médica Portuguesa |
| Online Access: | https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/2781 |
| _version_ | 1811242526554718208 |
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| author | J C de Almeida A Bettencourt C S Costa J M de Almeida |
| author_facet | J C de Almeida A Bettencourt C S Costa J M de Almeida |
| author_sort | J C de Almeida |
| collection | DOAJ |
| description | Periampullary tumors form a clinical entity with common symptoms, similar therapeutic options, unsatisfactory resectability rates and unfavorable prognosis. From April 1970 until March 1994, one hundred and twenty-seven patients with periampullary carcinoma were operated by our surgical team. In 48 of these patients, a resection for cure was performed (38%). Resectability rates varied according to the origin of these tumors, i.e., pancreas-20%, ampulla-76%; distal bile duct-71%, periampullary duodenum-88%. Pancreatic tumors showed a different resectability rate from the other periampullary carcinomas (p = 0.04). Forty-two of these patients had a pancreatoduodenectomy and in the remaining 6 cases a total pancreatectomy was performed. Fifteen patients had major post-operative morbidity (31%) and 8 of these cases died in-hospital (17%). Follow-up data was available in 81% of the patients, survival estimates were calculated according to the Kaplan-Meier method and survival comparisons were made with the Log-rank test. Median survival for resected pancreatic carcinoma was 6 months and for resected tumors of the ampulla 37 months. In this group of patients, pancreatic tumors showed a different survival rate from the remaining periampullary tumors (Log-rank-p = 0.002). This work evidences the need to improve management of periampullary tumors, particularly in-hospital mortality and long-term survival. To achieve these goals, patients with periampullary tumors should be treated in specialized centers and research to improve local and systemic control of this disease should be pursued. |
| first_indexed | 2024-04-12T13:52:32Z |
| format | Article |
| id | doaj.art-d3d530bc4b0b48ab8a2b5af4d5cdb719 |
| institution | Directory Open Access Journal |
| issn | 0870-399X 1646-0758 |
| language | English |
| last_indexed | 2024-04-12T13:52:32Z |
| publishDate | 1995-12-01 |
| publisher | Ordem dos Médicos |
| record_format | Article |
| series | Acta Médica Portuguesa |
| spelling | doaj.art-d3d530bc4b0b48ab8a2b5af4d5cdb7192022-12-22T03:30:29ZengOrdem dos MédicosActa Médica Portuguesa0870-399X1646-07581995-12-01810.20344/amp.2781Cirurgia de intenção curativa nos tumores peri-ampulares. Resultados de 48 ressecções consecutivas.J C de Almeida0A BettencourtC S CostaJ M de AlmeidaClínica Oncológica III, Instituto Português de Oncologia de Francisco Gentil, Lisboa.Periampullary tumors form a clinical entity with common symptoms, similar therapeutic options, unsatisfactory resectability rates and unfavorable prognosis. From April 1970 until March 1994, one hundred and twenty-seven patients with periampullary carcinoma were operated by our surgical team. In 48 of these patients, a resection for cure was performed (38%). Resectability rates varied according to the origin of these tumors, i.e., pancreas-20%, ampulla-76%; distal bile duct-71%, periampullary duodenum-88%. Pancreatic tumors showed a different resectability rate from the other periampullary carcinomas (p = 0.04). Forty-two of these patients had a pancreatoduodenectomy and in the remaining 6 cases a total pancreatectomy was performed. Fifteen patients had major post-operative morbidity (31%) and 8 of these cases died in-hospital (17%). Follow-up data was available in 81% of the patients, survival estimates were calculated according to the Kaplan-Meier method and survival comparisons were made with the Log-rank test. Median survival for resected pancreatic carcinoma was 6 months and for resected tumors of the ampulla 37 months. In this group of patients, pancreatic tumors showed a different survival rate from the remaining periampullary tumors (Log-rank-p = 0.002). This work evidences the need to improve management of periampullary tumors, particularly in-hospital mortality and long-term survival. To achieve these goals, patients with periampullary tumors should be treated in specialized centers and research to improve local and systemic control of this disease should be pursued.https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/2781 |
| spellingShingle | J C de Almeida A Bettencourt C S Costa J M de Almeida Cirurgia de intenção curativa nos tumores peri-ampulares. Resultados de 48 ressecções consecutivas. Acta Médica Portuguesa |
| title | Cirurgia de intenção curativa nos tumores peri-ampulares. Resultados de 48 ressecções consecutivas. |
| title_full | Cirurgia de intenção curativa nos tumores peri-ampulares. Resultados de 48 ressecções consecutivas. |
| title_fullStr | Cirurgia de intenção curativa nos tumores peri-ampulares. Resultados de 48 ressecções consecutivas. |
| title_full_unstemmed | Cirurgia de intenção curativa nos tumores peri-ampulares. Resultados de 48 ressecções consecutivas. |
| title_short | Cirurgia de intenção curativa nos tumores peri-ampulares. Resultados de 48 ressecções consecutivas. |
| title_sort | cirurgia de intencao curativa nos tumores peri ampulares resultados de 48 resseccoes consecutivas |
| url | https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/2781 |
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