The impact of curcumin on migraine: A comprehensive review
Migraine, a neurovascular condition, is a chronic and lifelong disease that affects about 15% of the population worldwide. Although the exact pathophysiology and etiology of migraine are still unclear, oxidative stress, inflammation, and neuroendocrine imbalances are identified as the critical risk...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2023-08-01
|
| Series: | Biomedicine & Pharmacotherapy |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S075333222300700X |
| _version_ | 1797801869428391936 |
|---|---|
| author | Hajar Heidari Mehrnaz Shojaei Gholamreza Askari Muhammed Majeed Mohammad Bagherniya George E. Barreto Amirhossein Sahebkar |
| author_facet | Hajar Heidari Mehrnaz Shojaei Gholamreza Askari Muhammed Majeed Mohammad Bagherniya George E. Barreto Amirhossein Sahebkar |
| author_sort | Hajar Heidari |
| collection | DOAJ |
| description | Migraine, a neurovascular condition, is a chronic and lifelong disease that affects about 15% of the population worldwide. Although the exact pathophysiology and etiology of migraine are still unclear, oxidative stress, inflammation, and neuroendocrine imbalances are identified as the critical risk factors for migraine attacks. Curcumin is an active component and a polyphenolic diketone compound extracted from turmeric. Curcumin is a promising candidate for preventing and controlling migraine due to its anti‑inflammatory, antioxidative, anti-protein aggregate, and analgesic effects. In the present review, we have evaluated experimental and clinical studies investigating the impact of liposomal curcumin and nano-curcumin on the frequency and severity of migraine attacks in patients. Although the results are promising, more studies should be conducted in this area to show the exact efficacies of curcumin on clinical symptoms of migraine and investigate its potential mechanisms. |
| first_indexed | 2024-03-13T04:57:05Z |
| format | Article |
| id | doaj.art-d3d59ccf0a31498585799b877f7571f7 |
| institution | Directory Open Access Journal |
| issn | 0753-3322 |
| language | English |
| last_indexed | 2024-03-13T04:57:05Z |
| publishDate | 2023-08-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Biomedicine & Pharmacotherapy |
| spelling | doaj.art-d3d59ccf0a31498585799b877f7571f72023-06-18T05:00:40ZengElsevierBiomedicine & Pharmacotherapy0753-33222023-08-01164114910The impact of curcumin on migraine: A comprehensive reviewHajar Heidari0Mehrnaz Shojaei1Gholamreza Askari2Muhammed Majeed3Mohammad Bagherniya4George E. Barreto5Amirhossein Sahebkar6Food Security Research Center, Department of Clinical Nutrition, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, IranFood Security Research Center and Department of Community Nutrition, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, IranFood Security Research Center and Department of Community Nutrition, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, Iran; Anesthesia and Critical Care Research Center, Isfahan University of Medical Sciences, Isfahan, IranSabinsa Corporation, 20 Lake Drive, East Windsor, NJ, 08520, USAFood Security Research Center and Department of Community Nutrition, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, Iran; Anesthesia and Critical Care Research Center, Isfahan University of Medical Sciences, Isfahan, Iran; Corresponding author at: Food Security Research Center and Department of Community Nutrition, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, Iran.Department of Biological Sciences, University of Limerick, Limerick, Ireland; Corresponding author.Biotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran; Applied Biomedical Research Center, Mashhad University of Medical Sciences, Mashhad, Iran; Corresponding author at: Biotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran.Migraine, a neurovascular condition, is a chronic and lifelong disease that affects about 15% of the population worldwide. Although the exact pathophysiology and etiology of migraine are still unclear, oxidative stress, inflammation, and neuroendocrine imbalances are identified as the critical risk factors for migraine attacks. Curcumin is an active component and a polyphenolic diketone compound extracted from turmeric. Curcumin is a promising candidate for preventing and controlling migraine due to its anti‑inflammatory, antioxidative, anti-protein aggregate, and analgesic effects. In the present review, we have evaluated experimental and clinical studies investigating the impact of liposomal curcumin and nano-curcumin on the frequency and severity of migraine attacks in patients. Although the results are promising, more studies should be conducted in this area to show the exact efficacies of curcumin on clinical symptoms of migraine and investigate its potential mechanisms.http://www.sciencedirect.com/science/article/pii/S075333222300700XCurcuminMigraineOxidative stressInflammation |
| spellingShingle | Hajar Heidari Mehrnaz Shojaei Gholamreza Askari Muhammed Majeed Mohammad Bagherniya George E. Barreto Amirhossein Sahebkar The impact of curcumin on migraine: A comprehensive review Biomedicine & Pharmacotherapy Curcumin Migraine Oxidative stress Inflammation |
| title | The impact of curcumin on migraine: A comprehensive review |
| title_full | The impact of curcumin on migraine: A comprehensive review |
| title_fullStr | The impact of curcumin on migraine: A comprehensive review |
| title_full_unstemmed | The impact of curcumin on migraine: A comprehensive review |
| title_short | The impact of curcumin on migraine: A comprehensive review |
| title_sort | impact of curcumin on migraine a comprehensive review |
| topic | Curcumin Migraine Oxidative stress Inflammation |
| url | http://www.sciencedirect.com/science/article/pii/S075333222300700X |
| work_keys_str_mv | AT hajarheidari theimpactofcurcuminonmigraineacomprehensivereview AT mehrnazshojaei theimpactofcurcuminonmigraineacomprehensivereview AT gholamrezaaskari theimpactofcurcuminonmigraineacomprehensivereview AT muhammedmajeed theimpactofcurcuminonmigraineacomprehensivereview AT mohammadbagherniya theimpactofcurcuminonmigraineacomprehensivereview AT georgeebarreto theimpactofcurcuminonmigraineacomprehensivereview AT amirhosseinsahebkar theimpactofcurcuminonmigraineacomprehensivereview AT hajarheidari impactofcurcuminonmigraineacomprehensivereview AT mehrnazshojaei impactofcurcuminonmigraineacomprehensivereview AT gholamrezaaskari impactofcurcuminonmigraineacomprehensivereview AT muhammedmajeed impactofcurcuminonmigraineacomprehensivereview AT mohammadbagherniya impactofcurcuminonmigraineacomprehensivereview AT georgeebarreto impactofcurcuminonmigraineacomprehensivereview AT amirhosseinsahebkar impactofcurcuminonmigraineacomprehensivereview |