| Summary: | Global population growth is demanding for more food production in the future. The selection of the plant for cropping has led to the loss of valuable genotypes. Genome-editing technology is the recent advances in plant breeding which allows the insertion, deletion or substitution of the specific loci in the target host cell. Among the homologous recombination (HR) technology, transcription activation-like effector nuclease (TALEN), zinc finger nucleases (ZFN) and clustered regularly interspaced short palindromic repeats (CRISPR); the most popular these days is CRISPR/Cas. Here, we review the methods of genome-editing, their applications, potentials, and the regulatory issues related to genetically modified organisms.
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