Advantages of Whole Genome Sequencing in Mitigating the <i>Helicobacter pylori</i> Antimicrobial Resistance Problem
<i>Helicobacter pylori</i> antimicrobial resistance is a critical public health issue. Typically, antimicrobial resistance epidemiology reports include only the antimicrobial susceptibility test results for <i>H. pylori</i>. However, this phenotypic approach is less capable o...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-05-01
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| Series: | Microorganisms |
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| Online Access: | https://www.mdpi.com/2076-2607/11/5/1239 |
| _version_ | 1827740670122524672 |
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| author | Kartika Afrida Fauzia Ricky Indra Alfaray Yoshio Yamaoka |
| author_facet | Kartika Afrida Fauzia Ricky Indra Alfaray Yoshio Yamaoka |
| author_sort | Kartika Afrida Fauzia |
| collection | DOAJ |
| description | <i>Helicobacter pylori</i> antimicrobial resistance is a critical public health issue. Typically, antimicrobial resistance epidemiology reports include only the antimicrobial susceptibility test results for <i>H. pylori</i>. However, this phenotypic approach is less capable of answering queries related to resistance mechanisms and specific mutations found in particular global regions. Whole genome sequencing can help address these two questions while still offering quality control and is routinely validated against AST standards. A comprehensive understanding of the mechanisms of resistance should improve <i>H. pylori</i> eradication efforts and prevent gastric cancer. |
| first_indexed | 2024-03-11T03:28:49Z |
| format | Article |
| id | doaj.art-d3d65d2a35374f64a31c2ceac8828fc8 |
| institution | Directory Open Access Journal |
| issn | 2076-2607 |
| language | English |
| last_indexed | 2024-03-11T03:28:49Z |
| publishDate | 2023-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Microorganisms |
| spelling | doaj.art-d3d65d2a35374f64a31c2ceac8828fc82023-11-18T02:33:51ZengMDPI AGMicroorganisms2076-26072023-05-01115123910.3390/microorganisms11051239Advantages of Whole Genome Sequencing in Mitigating the <i>Helicobacter pylori</i> Antimicrobial Resistance ProblemKartika Afrida Fauzia0Ricky Indra Alfaray1Yoshio Yamaoka2Department of Environmental and Preventive Medicine, Oita University Faculty of Medicine, Yufu 879-5593, JapanDepartment of Environmental and Preventive Medicine, Oita University Faculty of Medicine, Yufu 879-5593, JapanDepartment of Environmental and Preventive Medicine, Oita University Faculty of Medicine, Yufu 879-5593, Japan<i>Helicobacter pylori</i> antimicrobial resistance is a critical public health issue. Typically, antimicrobial resistance epidemiology reports include only the antimicrobial susceptibility test results for <i>H. pylori</i>. However, this phenotypic approach is less capable of answering queries related to resistance mechanisms and specific mutations found in particular global regions. Whole genome sequencing can help address these two questions while still offering quality control and is routinely validated against AST standards. A comprehensive understanding of the mechanisms of resistance should improve <i>H. pylori</i> eradication efforts and prevent gastric cancer.https://www.mdpi.com/2076-2607/11/5/1239<i>Helicobacter pylori</i>whole genome sequencingantimicrobial resistanceinfectious disease |
| spellingShingle | Kartika Afrida Fauzia Ricky Indra Alfaray Yoshio Yamaoka Advantages of Whole Genome Sequencing in Mitigating the <i>Helicobacter pylori</i> Antimicrobial Resistance Problem Microorganisms <i>Helicobacter pylori</i> whole genome sequencing antimicrobial resistance infectious disease |
| title | Advantages of Whole Genome Sequencing in Mitigating the <i>Helicobacter pylori</i> Antimicrobial Resistance Problem |
| title_full | Advantages of Whole Genome Sequencing in Mitigating the <i>Helicobacter pylori</i> Antimicrobial Resistance Problem |
| title_fullStr | Advantages of Whole Genome Sequencing in Mitigating the <i>Helicobacter pylori</i> Antimicrobial Resistance Problem |
| title_full_unstemmed | Advantages of Whole Genome Sequencing in Mitigating the <i>Helicobacter pylori</i> Antimicrobial Resistance Problem |
| title_short | Advantages of Whole Genome Sequencing in Mitigating the <i>Helicobacter pylori</i> Antimicrobial Resistance Problem |
| title_sort | advantages of whole genome sequencing in mitigating the i helicobacter pylori i antimicrobial resistance problem |
| topic | <i>Helicobacter pylori</i> whole genome sequencing antimicrobial resistance infectious disease |
| url | https://www.mdpi.com/2076-2607/11/5/1239 |
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