Antidysbiotic prophylaxis and therapy of non-infectious colitis
The increasing incidence of dysbiosis and its pathogenic consequences naturally raises questions about the search for treatment and prevention. It is established that in the pathogenesis of non-infectious colitis the decisive role is played by dysbiosis, that is, the reduction of the level of prob...
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| Format: | Article |
| Language: | English |
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Kazimierz Wielki University
2019-02-01
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| Series: | Journal of Education, Health and Sport |
| Subjects: | |
| Online Access: | https://apcz.umk.pl/JEHS/article/view/29214 |
| _version_ | 1828366947364896768 |
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| author | A. V. Bocharov |
| author_facet | A. V. Bocharov |
| author_sort | A. V. Bocharov |
| collection | DOAJ |
| description |
The increasing incidence of dysbiosis and its pathogenic consequences naturally raises questions about the search for treatment and prevention.
It is established that in the pathogenesis of non-infectious colitis the decisive role is played by dysbiosis, that is, the reduction of the level of probiotic bacteria and the increase in the number of conditionally pathogenic species, especially their virulent strains. Under the conditions of functioning of the normal microbial composition of the microbiome, the probiotic bacteria exert a suppressive effect on the conditionally pathogenic microflora.
It is important that even with the development of dysbiosis only the ratio of the two groups of microorganisms changes, and, for example, the biotic bacteria do not completely disappear, which makes it possible to restore them.
The results of many years of experimental studies carried out in the laboratory of Professor AP Levitsky showed the antidysbiotic property of polyphenolic compounds, in particular bioflavonoids. It is known that bioflavonoids belong to plant substances and have a very wide range of biological effects: antioxidant, anti-enzyme, membrane-protecting, hepatoprotective, anti-dysbiotic, anti-inflammatory and therefore used for the treatment of many diseases, in the first place.
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| first_indexed | 2024-04-14T05:52:44Z |
| format | Article |
| id | doaj.art-d3daf970375f4fbc86def09d30fcc3bc |
| institution | Directory Open Access Journal |
| issn | 2391-8306 |
| language | English |
| last_indexed | 2024-04-14T05:52:44Z |
| publishDate | 2019-02-01 |
| publisher | Kazimierz Wielki University |
| record_format | Article |
| series | Journal of Education, Health and Sport |
| spelling | doaj.art-d3daf970375f4fbc86def09d30fcc3bc2022-12-22T02:09:04ZengKazimierz Wielki UniversityJournal of Education, Health and Sport2391-83062019-02-0192Antidysbiotic prophylaxis and therapy of non-infectious colitisA. V. Bocharov0HSEE of Ukraine “Bukovinian State Medical University” The increasing incidence of dysbiosis and its pathogenic consequences naturally raises questions about the search for treatment and prevention. It is established that in the pathogenesis of non-infectious colitis the decisive role is played by dysbiosis, that is, the reduction of the level of probiotic bacteria and the increase in the number of conditionally pathogenic species, especially their virulent strains. Under the conditions of functioning of the normal microbial composition of the microbiome, the probiotic bacteria exert a suppressive effect on the conditionally pathogenic microflora. It is important that even with the development of dysbiosis only the ratio of the two groups of microorganisms changes, and, for example, the biotic bacteria do not completely disappear, which makes it possible to restore them. The results of many years of experimental studies carried out in the laboratory of Professor AP Levitsky showed the antidysbiotic property of polyphenolic compounds, in particular bioflavonoids. It is known that bioflavonoids belong to plant substances and have a very wide range of biological effects: antioxidant, anti-enzyme, membrane-protecting, hepatoprotective, anti-dysbiotic, anti-inflammatory and therefore used for the treatment of many diseases, in the first place. https://apcz.umk.pl/JEHS/article/view/29214dysbiosiscolitisprobioticsprevention |
| spellingShingle | A. V. Bocharov Antidysbiotic prophylaxis and therapy of non-infectious colitis Journal of Education, Health and Sport dysbiosis colitis probiotics prevention |
| title | Antidysbiotic prophylaxis and therapy of non-infectious colitis |
| title_full | Antidysbiotic prophylaxis and therapy of non-infectious colitis |
| title_fullStr | Antidysbiotic prophylaxis and therapy of non-infectious colitis |
| title_full_unstemmed | Antidysbiotic prophylaxis and therapy of non-infectious colitis |
| title_short | Antidysbiotic prophylaxis and therapy of non-infectious colitis |
| title_sort | antidysbiotic prophylaxis and therapy of non infectious colitis |
| topic | dysbiosis colitis probiotics prevention |
| url | https://apcz.umk.pl/JEHS/article/view/29214 |
| work_keys_str_mv | AT avbocharov antidysbioticprophylaxisandtherapyofnoninfectiouscolitis |