Case Report: Ductal Carcinoma in Situ Within A Granulomatous Mastitis
Granulomatous lobular mastitis is a rare chronic breast disease, firstly described by Kessler and Wolloch in 1972. In this article we present a 35-yearold patient with granulomatous lobular mastitis and in situ ductal carcinoma and discuss clinicopathological characteristics of the disease with lite...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Galenos Publishing House
2018-07-01
|
| Series: | European Journal of Breast Health |
| Subjects: | |
| Online Access: |
http://www.eurjbreasthealth.com/archives/archive-detail/article-preview/case-report-ductal-carcinoma-in-situ-within-a-gran/42043
|
| _version_ | 1828019721078833152 |
|---|---|
| author | Mine Özşen Şahsine Tolunay M. Şehsuvar Gökgöz |
| author_facet | Mine Özşen Şahsine Tolunay M. Şehsuvar Gökgöz |
| author_sort | Mine Özşen |
| collection | DOAJ |
| description | Granulomatous lobular mastitis is a rare chronic breast disease, firstly described by Kessler and Wolloch in 1972. In this article we present a 35-yearold patient with granulomatous lobular mastitis and in situ ductal carcinoma and discuss clinicopathological characteristics of the disease with literature data. A 35-year-old female patient admitted to the outpatient clinic with a complaint of swelling in right breast ongoing since March 2017. On the basis of physical examination and radiological examinations, antibiotic therapy was initiated considering the inflammatory breast disease and the patient was referred to our general surgery clinic because she did not benefit from treatment. On the recommendation of histopathological correlation, trucut biopsy was performed and reported as granulomatous mastitis. In the histopathological examination of the prepared sections, we found lobule-restricted, non-caseous granulomas and neoplastic epithelial cell proliferation in 4 different foci, the largest being 0.7x0.4 cm in diameter, limited to the ductal lobular system. The case was diagnosed as granulomatous lobular mastitis and in situ ductal carcinoma. This lesion, which clinically and radiologically can be confused with carcinoma, rarely coexists with breast carcinoma. Our case demonstrates the coexistence of granulomatous lobular mastitis and in situ ductal carcinoma. |
| first_indexed | 2024-04-10T11:24:53Z |
| format | Article |
| id | doaj.art-d3e0038dfec04912aeb27b15305bcd75 |
| institution | Directory Open Access Journal |
| issn | 2587-0831 |
| language | English |
| last_indexed | 2024-04-10T11:24:53Z |
| publishDate | 2018-07-01 |
| publisher | Galenos Publishing House |
| record_format | Article |
| series | European Journal of Breast Health |
| spelling | doaj.art-d3e0038dfec04912aeb27b15305bcd752023-02-15T16:18:30ZengGalenos Publishing HouseEuropean Journal of Breast Health2587-08312018-07-0114318618810.5152/ejbh.2018.389413049054Case Report: Ductal Carcinoma in Situ Within A Granulomatous MastitisMine Özşen0Şahsine Tolunay1M. Şehsuvar Gökgöz2 Department of Pathology, Uludağ University School of Medicine, Bursa, Turkey Department of Pathology, Uludağ University School of Medicine, Bursa, Turkey Department of Breast Surgery, Uludag University School of Medicine, Bursa, Turkey Granulomatous lobular mastitis is a rare chronic breast disease, firstly described by Kessler and Wolloch in 1972. In this article we present a 35-yearold patient with granulomatous lobular mastitis and in situ ductal carcinoma and discuss clinicopathological characteristics of the disease with literature data. A 35-year-old female patient admitted to the outpatient clinic with a complaint of swelling in right breast ongoing since March 2017. On the basis of physical examination and radiological examinations, antibiotic therapy was initiated considering the inflammatory breast disease and the patient was referred to our general surgery clinic because she did not benefit from treatment. On the recommendation of histopathological correlation, trucut biopsy was performed and reported as granulomatous mastitis. In the histopathological examination of the prepared sections, we found lobule-restricted, non-caseous granulomas and neoplastic epithelial cell proliferation in 4 different foci, the largest being 0.7x0.4 cm in diameter, limited to the ductal lobular system. The case was diagnosed as granulomatous lobular mastitis and in situ ductal carcinoma. This lesion, which clinically and radiologically can be confused with carcinoma, rarely coexists with breast carcinoma. Our case demonstrates the coexistence of granulomatous lobular mastitis and in situ ductal carcinoma. http://www.eurjbreasthealth.com/archives/archive-detail/article-preview/case-report-ductal-carcinoma-in-situ-within-a-gran/42043 chronic breast inflammationductal carcinoma in situgranulomatous inflammationgranulomatous lobular mastitis |
| spellingShingle | Mine Özşen Şahsine Tolunay M. Şehsuvar Gökgöz Case Report: Ductal Carcinoma in Situ Within A Granulomatous Mastitis European Journal of Breast Health chronic breast inflammation ductal carcinoma in situ granulomatous inflammation granulomatous lobular mastitis |
| title | Case Report: Ductal Carcinoma in Situ Within A Granulomatous Mastitis |
| title_full | Case Report: Ductal Carcinoma in Situ Within A Granulomatous Mastitis |
| title_fullStr | Case Report: Ductal Carcinoma in Situ Within A Granulomatous Mastitis |
| title_full_unstemmed | Case Report: Ductal Carcinoma in Situ Within A Granulomatous Mastitis |
| title_short | Case Report: Ductal Carcinoma in Situ Within A Granulomatous Mastitis |
| title_sort | case report ductal carcinoma in situ within a granulomatous mastitis |
| topic | chronic breast inflammation ductal carcinoma in situ granulomatous inflammation granulomatous lobular mastitis |
| url |
http://www.eurjbreasthealth.com/archives/archive-detail/article-preview/case-report-ductal-carcinoma-in-situ-within-a-gran/42043
|
| work_keys_str_mv | AT mineozsen casereportductalcarcinomainsituwithinagranulomatousmastitis AT sahsinetolunay casereportductalcarcinomainsituwithinagranulomatousmastitis AT msehsuvargokgoz casereportductalcarcinomainsituwithinagranulomatousmastitis |