Analysis of the impact of DGAT1 p.M435L and p.K232A variants on pre-mRNA splicing in a full-length gene assay
Abstract DGAT1 is playing a major role in fat metabolism and triacylglyceride synthesis. Only two DGAT1 loss-of-function variants altering milk production traits in cattle have been reported to date, namely p.M435L and p.K232A. The p.M435L variant is a rare alteration and has been associated with sk...
Main Authors: | Nicolas Gaiani, Lorraine Bourgeois-Brunel, Dominique Rocha, Arnaud Boulling |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-06-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-023-36142-z |
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