Electrochemically generated acid and its containment to 100 micron reaction areas for the production of DNA microarrays.

Electrochemically generated acid and its containment to 100 micron reaction areas for the production of DNA microarrays.

An addressable electrode array was used for the production of acid at sufficient concentration to allow deprotection of the dimethoxytrityl (DMT) protecting group from an overlaying substrate bound to a porous reaction layer. Containment of the generated acid to an active electrode of 100 micron dia...

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Bibliographic Details
Main Authors: Karl Maurer, John Cooper, Marcelo Caraballo, James Crye, Dominic Suciu, Andrey Ghindilis, Joseph A Leonetti, Wei Wang, Francis M Rossi, Axel G Stöver, Christopher Larson, Hetian Gao, Kilian Dill, Andy McShea
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC1762329?pdf=render

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