QUALITATIVE CHEMICAL PROFILE AND BIOLOGICAL ACTIVITY OF BROWNEA GRANDICEPS JACQ. (FABACEAE) LEAVES AND STEMS EXTRACTS
The hexane, dichloromethane, and methanol extracts obtained from aerial parts of Brownea grandiceps Jacq (Fabaceae) were studied to determine the antioxidant and tick control activity. The qualitative chemical composition showed the presence of sterols in hexane and dichloromethane extracts of le...
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| Format: | Article |
| Language: | English |
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Editura Universităţii din Oradea
2022-11-01
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| Series: | Natural Resources and Sustainable Development |
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| Online Access: | https://docs.google.com/viewerng/viewer?url=http://nrsdj.com/papers/2022-2/09.+Gonzalez+Daisy.pdf |
| _version_ | 1797859246012891136 |
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| author | González Daisy* Rojas Janne** Visbal Tomas* Morillo Marielba* |
| author_facet | González Daisy* Rojas Janne** Visbal Tomas* Morillo Marielba* |
| author_sort | González Daisy* |
| collection | DOAJ |
| description | The hexane, dichloromethane, and methanol extracts obtained from aerial parts of Brownea
grandiceps Jacq (Fabaceae) were studied to determine the antioxidant and tick control activity. The
qualitative chemical composition showed the presence of sterols in hexane and dichloromethane
extracts of leaves while in methanol extract were observed alkaloids, sterols, polyphenols, tannins, and
flavonoids. Furthermore, hexane extract of stems revealed the presence of terpenes; dichloromethane
extract showed sterols whereas methanol extract exhibited the presence of alkaloids, polyphenols,
tannins, and flavonoids. On the other hand, phenolic compounds were observed in methanol extract of
leaves and stems of this species with values of 0.888 and 0.886 μg GAE/mg of extract, respectively.
Regarding the scavenging capacity measured the by DPPH method, methanol extracts of leaves and
stems showed the highest value at a concentration of 0.5 mg/mL with percentages of inhibition (% I) of
89.2 and 88.9 respectively. However, a much lower activity was observed with hexane extract of the
leaves with a % I of 20.1 at the same concentration. Regarding inverse of effective concentration assay,
methanol extract of leaves and stems showed values of 10.0 and 7.14 mL/mg. In addition, methanol
extracts of leaves and stems of B. grandiceps did not show activity on the larvae of Riphicephalus
microplus. |
| first_indexed | 2024-04-09T21:26:23Z |
| format | Article |
| id | doaj.art-d3e55480709341bd9c13f42bd3c8a836 |
| institution | Directory Open Access Journal |
| issn | 2066-6276 2601-5676 |
| language | English |
| last_indexed | 2024-04-09T21:26:23Z |
| publishDate | 2022-11-01 |
| publisher | Editura Universităţii din Oradea |
| record_format | Article |
| series | Natural Resources and Sustainable Development |
| spelling | doaj.art-d3e55480709341bd9c13f42bd3c8a8362023-03-27T13:52:10ZengEditura Universităţii din OradeaNatural Resources and Sustainable Development2066-62762601-56762022-11-0112231332810.31924/nrsd.v12i2.108QUALITATIVE CHEMICAL PROFILE AND BIOLOGICAL ACTIVITY OF BROWNEA GRANDICEPS JACQ. (FABACEAE) LEAVES AND STEMS EXTRACTSGonzález Daisy*0Rojas Janne**1Visbal Tomas*2Morillo Marielba*3*University of Los Andes, Faculty of Pharmacy and Bioanalysis, Ecology and Nutrition Research Group, Mérida 5101, Venezuela**University of Los Andes, Faculty of Pharmacy and Bioanalysis, Organic Biomolecular Research Group, Mérida 5101, Venezuela*University of Los Andes, Faculty of Pharmacy and Bioanalysis, Ecology and Nutrition Research Group, Mérida 5101, Venezuela*University of Los Andes, Faculty of Pharmacy and Bioanalysis, Ecology and Nutrition Research Group, Mérida 5101, VenezuelaThe hexane, dichloromethane, and methanol extracts obtained from aerial parts of Brownea grandiceps Jacq (Fabaceae) were studied to determine the antioxidant and tick control activity. The qualitative chemical composition showed the presence of sterols in hexane and dichloromethane extracts of leaves while in methanol extract were observed alkaloids, sterols, polyphenols, tannins, and flavonoids. Furthermore, hexane extract of stems revealed the presence of terpenes; dichloromethane extract showed sterols whereas methanol extract exhibited the presence of alkaloids, polyphenols, tannins, and flavonoids. On the other hand, phenolic compounds were observed in methanol extract of leaves and stems of this species with values of 0.888 and 0.886 μg GAE/mg of extract, respectively. Regarding the scavenging capacity measured the by DPPH method, methanol extracts of leaves and stems showed the highest value at a concentration of 0.5 mg/mL with percentages of inhibition (% I) of 89.2 and 88.9 respectively. However, a much lower activity was observed with hexane extract of the leaves with a % I of 20.1 at the same concentration. Regarding inverse of effective concentration assay, methanol extract of leaves and stems showed values of 10.0 and 7.14 mL/mg. In addition, methanol extracts of leaves and stems of B. grandiceps did not show activity on the larvae of Riphicephalus microplus.https://docs.google.com/viewerng/viewer?url=http://nrsdj.com/papers/2022-2/09.+Gonzalez+Daisy.pdfbrownea grandiceps jacqfabaceaedpphphenols contentriphicephalus microplus |
| spellingShingle | González Daisy* Rojas Janne** Visbal Tomas* Morillo Marielba* QUALITATIVE CHEMICAL PROFILE AND BIOLOGICAL ACTIVITY OF BROWNEA GRANDICEPS JACQ. (FABACEAE) LEAVES AND STEMS EXTRACTS Natural Resources and Sustainable Development brownea grandiceps jacq fabaceae dpph phenols content riphicephalus microplus |
| title | QUALITATIVE CHEMICAL PROFILE AND BIOLOGICAL ACTIVITY OF BROWNEA GRANDICEPS JACQ. (FABACEAE) LEAVES AND STEMS EXTRACTS |
| title_full | QUALITATIVE CHEMICAL PROFILE AND BIOLOGICAL ACTIVITY OF BROWNEA GRANDICEPS JACQ. (FABACEAE) LEAVES AND STEMS EXTRACTS |
| title_fullStr | QUALITATIVE CHEMICAL PROFILE AND BIOLOGICAL ACTIVITY OF BROWNEA GRANDICEPS JACQ. (FABACEAE) LEAVES AND STEMS EXTRACTS |
| title_full_unstemmed | QUALITATIVE CHEMICAL PROFILE AND BIOLOGICAL ACTIVITY OF BROWNEA GRANDICEPS JACQ. (FABACEAE) LEAVES AND STEMS EXTRACTS |
| title_short | QUALITATIVE CHEMICAL PROFILE AND BIOLOGICAL ACTIVITY OF BROWNEA GRANDICEPS JACQ. (FABACEAE) LEAVES AND STEMS EXTRACTS |
| title_sort | qualitative chemical profile and biological activity of brownea grandiceps jacq fabaceae leaves and stems extracts |
| topic | brownea grandiceps jacq fabaceae dpph phenols content riphicephalus microplus |
| url | https://docs.google.com/viewerng/viewer?url=http://nrsdj.com/papers/2022-2/09.+Gonzalez+Daisy.pdf |
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