Diabetes Mellitus and Its Associated Factors in Tuberculosis Patients in Maekel Region, Eritrea: Analytical Cross-Sectional Study
Zenawi Zeramariam Araia,1 Araia Berhane Mesfin,2 Amanuel Hadgu Mebrahtu,1 Adiam Ghebreyohanns Tewelde,3 Randa Osman,4 Hagos Andom Tuumzghi5 1National TB and Leprosy Control Program, Communicable Disease Control Division, Ministry of Health, Asmara, Eritrea; 2Communicable Diseases Control Division, M...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Dove Medical Press
2021-02-01
|
| Series: | Diabetes, Metabolic Syndrome and Obesity |
| Subjects: | |
| Online Access: | https://www.dovepress.com/diabetes-mellitus-and-its-associated-factors-in-tuberculosis-patients--peer-reviewed-article-DMSO |
| _version_ | 1797935279051374592 |
|---|---|
| author | Araia ZZ Mesfin AB Mebrahtu AH Tewelde AG Osman R Tuumzghi HA |
| author_facet | Araia ZZ Mesfin AB Mebrahtu AH Tewelde AG Osman R Tuumzghi HA |
| author_sort | Araia ZZ |
| collection | DOAJ |
| description | Zenawi Zeramariam Araia,1 Araia Berhane Mesfin,2 Amanuel Hadgu Mebrahtu,1 Adiam Ghebreyohanns Tewelde,3 Randa Osman,4 Hagos Andom Tuumzghi5 1National TB and Leprosy Control Program, Communicable Disease Control Division, Ministry of Health, Asmara, Eritrea; 2Communicable Diseases Control Division, Ministry of Health, Asmara, Eritrea; 3Integrated Disease Surveillance and Response, Ministry of Health, Asmara, Eritrea; 4Orrota College of Medicine and Health Sciences, Asmara, Eritrea; 5Ministry of Health, Maekel Region Branch, Asmara, EritreaCorrespondence: Zenawi Zeramariam AraiaNational TB and Leprosy Control Program, Communicable Diseases Control Division, Ministry of Health, Asmara, EritreaTel +291-1-122129Email zenhopncl@gmail.comBackground: Both diabetes mellitus (DM) and tuberculosis (TB) are among the leading causes of morbidity and mortality in Eritrea. TB-DM comorbidity is known to complicate TB care, control and prevention. However, systematically studied epidemiological data on TB-DM comorbidity and its associated risk factors are lacking in this country.Objective: This study aimed to assess the prevalence of DM and its associated factors among TB patients in the Maekel region, Eritrea.Methods: Analytical cross-sectional study was conducted in eleven TB diagnostic and treatment sites. Pretested data extraction tool was used to collect data from medical records. Prevalence data were analysed using frequencies, proportions and median. To determine DM risk factors, univariable and multivariable logistic regression analysis was done with 95% CI and p value < 0.05 considered significant.Results: Out of total eligible (1134) TB cases, DM prevalence was 9.88%. Age and BMI were identified as independent risk factors for DM among TB patients. Higher odds of DM were found among TB patients aged 45– 54 (aOR: 4.85[1.39– 16.94], p= 0.013) and those ≥ 55 (aOR: 6.99[2.12– 23.04], p= 0.001). TB cases with normal BMI were two times more likely to have DM (aOR: 2.00[1.23– 3.26], p= 0.005) compared to those underweight.Conclusion: The prevalence of DM among TB cases observed in this study is high, a clarion call to scale up current efforts to integrate TB-DM services within routine care. Furthermore, age and BMI were identified as independent risk factors for DM in TB cases, pointing to the need to pay attention to age and BMI status when managing this co-morbidity.Keywords: TB-DM prevalence, transient hyperglycaemia, fasting blood glucose, pre-diabetes, Eritrea |
| first_indexed | 2024-04-10T18:11:53Z |
| format | Article |
| id | doaj.art-d3e5ffe533f641729b6be6665056a1a6 |
| institution | Directory Open Access Journal |
| issn | 1178-7007 |
| language | English |
| last_indexed | 2024-04-10T18:11:53Z |
| publishDate | 2021-02-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Diabetes, Metabolic Syndrome and Obesity |
| spelling | doaj.art-d3e5ffe533f641729b6be6665056a1a62023-02-02T10:41:13ZengDove Medical PressDiabetes, Metabolic Syndrome and Obesity1178-70072021-02-01Volume 1451552361760Diabetes Mellitus and Its Associated Factors in Tuberculosis Patients in Maekel Region, Eritrea: Analytical Cross-Sectional StudyAraia ZZMesfin ABMebrahtu AHTewelde AGOsman RTuumzghi HAZenawi Zeramariam Araia,1 Araia Berhane Mesfin,2 Amanuel Hadgu Mebrahtu,1 Adiam Ghebreyohanns Tewelde,3 Randa Osman,4 Hagos Andom Tuumzghi5 1National TB and Leprosy Control Program, Communicable Disease Control Division, Ministry of Health, Asmara, Eritrea; 2Communicable Diseases Control Division, Ministry of Health, Asmara, Eritrea; 3Integrated Disease Surveillance and Response, Ministry of Health, Asmara, Eritrea; 4Orrota College of Medicine and Health Sciences, Asmara, Eritrea; 5Ministry of Health, Maekel Region Branch, Asmara, EritreaCorrespondence: Zenawi Zeramariam AraiaNational TB and Leprosy Control Program, Communicable Diseases Control Division, Ministry of Health, Asmara, EritreaTel +291-1-122129Email zenhopncl@gmail.comBackground: Both diabetes mellitus (DM) and tuberculosis (TB) are among the leading causes of morbidity and mortality in Eritrea. TB-DM comorbidity is known to complicate TB care, control and prevention. However, systematically studied epidemiological data on TB-DM comorbidity and its associated risk factors are lacking in this country.Objective: This study aimed to assess the prevalence of DM and its associated factors among TB patients in the Maekel region, Eritrea.Methods: Analytical cross-sectional study was conducted in eleven TB diagnostic and treatment sites. Pretested data extraction tool was used to collect data from medical records. Prevalence data were analysed using frequencies, proportions and median. To determine DM risk factors, univariable and multivariable logistic regression analysis was done with 95% CI and p value < 0.05 considered significant.Results: Out of total eligible (1134) TB cases, DM prevalence was 9.88%. Age and BMI were identified as independent risk factors for DM among TB patients. Higher odds of DM were found among TB patients aged 45– 54 (aOR: 4.85[1.39– 16.94], p= 0.013) and those ≥ 55 (aOR: 6.99[2.12– 23.04], p= 0.001). TB cases with normal BMI were two times more likely to have DM (aOR: 2.00[1.23– 3.26], p= 0.005) compared to those underweight.Conclusion: The prevalence of DM among TB cases observed in this study is high, a clarion call to scale up current efforts to integrate TB-DM services within routine care. Furthermore, age and BMI were identified as independent risk factors for DM in TB cases, pointing to the need to pay attention to age and BMI status when managing this co-morbidity.Keywords: TB-DM prevalence, transient hyperglycaemia, fasting blood glucose, pre-diabetes, Eritreahttps://www.dovepress.com/diabetes-mellitus-and-its-associated-factors-in-tuberculosis-patients--peer-reviewed-article-DMSOtb-dm prevalencetransient hyperglycaemiafasting blood glucosepre-diabeteseritrea |
| spellingShingle | Araia ZZ Mesfin AB Mebrahtu AH Tewelde AG Osman R Tuumzghi HA Diabetes Mellitus and Its Associated Factors in Tuberculosis Patients in Maekel Region, Eritrea: Analytical Cross-Sectional Study Diabetes, Metabolic Syndrome and Obesity tb-dm prevalence transient hyperglycaemia fasting blood glucose pre-diabetes eritrea |
| title | Diabetes Mellitus and Its Associated Factors in Tuberculosis Patients in Maekel Region, Eritrea: Analytical Cross-Sectional Study |
| title_full | Diabetes Mellitus and Its Associated Factors in Tuberculosis Patients in Maekel Region, Eritrea: Analytical Cross-Sectional Study |
| title_fullStr | Diabetes Mellitus and Its Associated Factors in Tuberculosis Patients in Maekel Region, Eritrea: Analytical Cross-Sectional Study |
| title_full_unstemmed | Diabetes Mellitus and Its Associated Factors in Tuberculosis Patients in Maekel Region, Eritrea: Analytical Cross-Sectional Study |
| title_short | Diabetes Mellitus and Its Associated Factors in Tuberculosis Patients in Maekel Region, Eritrea: Analytical Cross-Sectional Study |
| title_sort | diabetes mellitus and its associated factors in tuberculosis patients in maekel region eritrea analytical cross sectional study |
| topic | tb-dm prevalence transient hyperglycaemia fasting blood glucose pre-diabetes eritrea |
| url | https://www.dovepress.com/diabetes-mellitus-and-its-associated-factors-in-tuberculosis-patients--peer-reviewed-article-DMSO |
| work_keys_str_mv | AT araiazz diabetesmellitusanditsassociatedfactorsintuberculosispatientsinmaekelregioneritreaanalyticalcrosssectionalstudy AT mesfinab diabetesmellitusanditsassociatedfactorsintuberculosispatientsinmaekelregioneritreaanalyticalcrosssectionalstudy AT mebrahtuah diabetesmellitusanditsassociatedfactorsintuberculosispatientsinmaekelregioneritreaanalyticalcrosssectionalstudy AT teweldeag diabetesmellitusanditsassociatedfactorsintuberculosispatientsinmaekelregioneritreaanalyticalcrosssectionalstudy AT osmanr diabetesmellitusanditsassociatedfactorsintuberculosispatientsinmaekelregioneritreaanalyticalcrosssectionalstudy AT tuumzghiha diabetesmellitusanditsassociatedfactorsintuberculosispatientsinmaekelregioneritreaanalyticalcrosssectionalstudy |