Typical electronegative electroretinography and nyctalopia as a presenting feature of systemic malignant melanoma
Abby Vercio, KV Chalam, Timothy WinterDepartment of Ophthalmology, Loma Linda University School of Medicine, Loma Linda, CA, USAAbstract: We report a unique case of a female who presented with unilateral disk edema, melanoma-associated retinopathy symptoms, and suggestive electroretinography finding...
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2019-08-01
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| Series: | International Medical Case Reports Journal |
| Subjects: | |
| Online Access: | https://www.dovepress.com/typical-electronegative-electroretinography-and-nyctalopia-as-a-presen-peer-reviewed-article-IMCRJ |
| _version_ | 1818510468375904256 |
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| author | Vercio A Chalam KV Winter T |
| author_facet | Vercio A Chalam KV Winter T |
| author_sort | Vercio A |
| collection | DOAJ |
| description | Abby Vercio, KV Chalam, Timothy WinterDepartment of Ophthalmology, Loma Linda University School of Medicine, Loma Linda, CA, USAAbstract: We report a unique case of a female who presented with unilateral disk edema, melanoma-associated retinopathy symptoms, and suggestive electroretinography findings preceding a diagnosis of metastatic melanoma of the pelvis. A 63-year-old female presented with complaints of seeing shimmering lights and nyctalopia, and underwent an extensive ophthalmological and electrophysiological examination. Best-corrected visual acuity was 20/20 in both eyes. Visual fields showed relative central scotomata and concentric narrowing. Slit-lamp and fundus examinations were normal. Rod-specific electroretinography responses were severely reduced, with electronegative maximal combined rod–cone responses and delayed cone responses with normal amplitude. Melanoma-associated retinopathy was suspected. Extensive systemic and internal evaluation revealed occult metastatic melanoma of the pelvis of unknown primary site.Keywords: nyctalopia, ERG, S cone syndrome, melanoma |
| first_indexed | 2024-12-10T23:20:20Z |
| format | Article |
| id | doaj.art-d3e62a02092a43a3b77bb979dc5c54cd |
| institution | Directory Open Access Journal |
| issn | 1179-142X |
| language | English |
| last_indexed | 2024-12-10T23:20:20Z |
| publishDate | 2019-08-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | International Medical Case Reports Journal |
| spelling | doaj.art-d3e62a02092a43a3b77bb979dc5c54cd2022-12-22T01:29:44ZengDove Medical PressInternational Medical Case Reports Journal1179-142X2019-08-01Volume 1226527647829Typical electronegative electroretinography and nyctalopia as a presenting feature of systemic malignant melanomaVercio AChalam KVWinter TAbby Vercio, KV Chalam, Timothy WinterDepartment of Ophthalmology, Loma Linda University School of Medicine, Loma Linda, CA, USAAbstract: We report a unique case of a female who presented with unilateral disk edema, melanoma-associated retinopathy symptoms, and suggestive electroretinography findings preceding a diagnosis of metastatic melanoma of the pelvis. A 63-year-old female presented with complaints of seeing shimmering lights and nyctalopia, and underwent an extensive ophthalmological and electrophysiological examination. Best-corrected visual acuity was 20/20 in both eyes. Visual fields showed relative central scotomata and concentric narrowing. Slit-lamp and fundus examinations were normal. Rod-specific electroretinography responses were severely reduced, with electronegative maximal combined rod–cone responses and delayed cone responses with normal amplitude. Melanoma-associated retinopathy was suspected. Extensive systemic and internal evaluation revealed occult metastatic melanoma of the pelvis of unknown primary site.Keywords: nyctalopia, ERG, S cone syndrome, melanomahttps://www.dovepress.com/typical-electronegative-electroretinography-and-nyctalopia-as-a-presen-peer-reviewed-article-IMCRJElectronegative ERGMelanoma associated retinopathynyctalopiaMalignant Melanoma |
| spellingShingle | Vercio A Chalam KV Winter T Typical electronegative electroretinography and nyctalopia as a presenting feature of systemic malignant melanoma International Medical Case Reports Journal Electronegative ERG Melanoma associated retinopathy nyctalopia Malignant Melanoma |
| title | Typical electronegative electroretinography and nyctalopia as a presenting feature of systemic malignant melanoma |
| title_full | Typical electronegative electroretinography and nyctalopia as a presenting feature of systemic malignant melanoma |
| title_fullStr | Typical electronegative electroretinography and nyctalopia as a presenting feature of systemic malignant melanoma |
| title_full_unstemmed | Typical electronegative electroretinography and nyctalopia as a presenting feature of systemic malignant melanoma |
| title_short | Typical electronegative electroretinography and nyctalopia as a presenting feature of systemic malignant melanoma |
| title_sort | typical electronegative electroretinography and nyctalopia as a presenting feature of systemic malignant melanoma |
| topic | Electronegative ERG Melanoma associated retinopathy nyctalopia Malignant Melanoma |
| url | https://www.dovepress.com/typical-electronegative-electroretinography-and-nyctalopia-as-a-presen-peer-reviewed-article-IMCRJ |
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