The role of single nucleotide polymorphisms of IL-1A -889C>T (rs1800587), TNF-A -238G>A (rs361525), and VDR TaqI (rs731236) on susceptibility to herniated nucleus pulposus: a systematic review and meta-analysis [version 3; peer review: 2 approved]

The role of single nucleotide polymorphisms of IL-1A -889C>T (rs1800587), TNF-A -238G>A (rs361525), and VDR TaqI (rs731236) on susceptibility to herniated nucleus pulposus: a systematic review and meta-analysis [version 3; peer review: 2 approved]

Background: The pathogenesis of herniated nucleus pulposus (HNP) is complex and may involve the wide variety of gene polymorphism. However, the reports from the existing studies are inconclusive. The objective of this study was to determine the role of single nucleotide polymorphisms (SNPs) in inter...

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Main Authors: Azharuddin Azharuddin, Muhammad Ilmawan, Jonny Karunia Fajar, Marhami Fahriani, Sukamto S. Mamada, Helnida Anggun Maliga, Firzan Nainu, Kuldeep Dhama, Harapan Harapan, Rahadyan Magetsari
Format: Article
Language:English
Published: F1000 Research Ltd 2021-08-01
Series:F1000Research
Online Access:https://f1000research.com/articles/10-419/v3

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