Role of TLR4 in the induction of inflammatory changes in adipocytes and macrophages
In obesity, high levels of saturated fatty acids (SFAs) contribute to adipose tissue inflammation and dysfunction. Obesity-induced macrophage infiltration leads to insulin resistance, but the adipocyte itself may play a role in generating the inflammatory milieu. Given our recent findings of the rol...
Main Authors: | K. McKernan, M. Varghese, R. Patel, K. Singer |
---|---|
Format: | Article |
Language: | English |
Published: |
Taylor & Francis Group
2020-01-01
|
Series: | Adipocyte |
Subjects: | |
Online Access: | http://dx.doi.org/10.1080/21623945.2020.1760674 |
Similar Items
-
Exosomes Derived From M2 Macrophages Facilitate Osteogenesis and Reduce Adipogenesis of BMSCs
by: Ziyi Li, et al.
Published: (2021-07-01) -
Evaluating Effect of Mesenchymal Stem Cells on Expression of TLR2 and TLR4
in Mouse DCs
by: Mohammad Hossein Karimi, et al.
Published: (2016-06-01) -
Expression of Siglec-E Alters the Proteome of Lipopolysaccharide (LPS)-Activated Macrophages but Does Not Affect LPS-Driven Cytokine Production or Toll-Like Receptor 4 Endocytosis
by: Manjula Nagala, et al.
Published: (2018-01-01) -
Melatonin suppresses bone marrow adiposity in ovariectomized rats by rescuing the imbalance between osteogenesis and adipogenesis through SIRT1 activation
by: Xiaoxiong Huang, et al.
Published: (2023-01-01) -
Cyclooxygenase-2 dependent metabolism of 20-HETE increases adiposity and adipocyte enlargement in mesenchymal stem cell-derived adipocytes
by: Dong Hyun Kim, et al.
Published: (2013-03-01)