Tuberculous corneal ulcer with hypopyon: A case report
This case report represents an unusual presentation of Mycobacterium tuberculosis-associated corneal ulcer with hypopyon. A 64-year-old man presented with a hypopyon corneal ulcer in the right eye. His corneal scrapings were negative, and the ulcer was not responding to empirical antimicrobial thera...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2020-01-01
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| Series: | Indian Journal of Ophthalmology |
| Subjects: | |
| Online Access: | http://www.ijo.in/article.asp?issn=0301-4738;year=2020;volume=68;issue=5;spage=922;epage=924;aulast= |
| _version_ | 1818538508338331648 |
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| author | Neethu Latiff Meena Lakshmipathy M K Janani Parthopratim Dutta Majumder |
| author_facet | Neethu Latiff Meena Lakshmipathy M K Janani Parthopratim Dutta Majumder |
| author_sort | Neethu Latiff |
| collection | DOAJ |
| description | This case report represents an unusual presentation of Mycobacterium tuberculosis-associated corneal ulcer with hypopyon. A 64-year-old man presented with a hypopyon corneal ulcer in the right eye. His corneal scrapings were negative, and the ulcer was not responding to empirical antimicrobial therapy. A real-time polymerase chain reaction from an aqueous aspirate of the right eye detected 422 copies of M. tuberculosis. Subsequent investigations revealed positive Mantoux and interferon-gamma release assay, supportive radiology. The patient was successfully treated with a course of antitubercular therapy and topical steroids. Hypopyon corneal ulcer, though a rare manifestation of ocular tuberculosis, should be considered in cases not responding to standard antimicrobial therapy. |
| first_indexed | 2024-12-11T21:29:51Z |
| format | Article |
| id | doaj.art-d3ea79f0a3e343bab35c1c58dc8b3701 |
| institution | Directory Open Access Journal |
| issn | 0301-4738 1998-3689 |
| language | English |
| last_indexed | 2024-12-11T21:29:51Z |
| publishDate | 2020-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Ophthalmology |
| spelling | doaj.art-d3ea79f0a3e343bab35c1c58dc8b37012022-12-22T00:50:13ZengWolters Kluwer Medknow PublicationsIndian Journal of Ophthalmology0301-47381998-36892020-01-0168592292410.4103/ijo.IJO_1368_19Tuberculous corneal ulcer with hypopyon: A case reportNeethu LatiffMeena LakshmipathyM K JananiParthopratim Dutta MajumderThis case report represents an unusual presentation of Mycobacterium tuberculosis-associated corneal ulcer with hypopyon. A 64-year-old man presented with a hypopyon corneal ulcer in the right eye. His corneal scrapings were negative, and the ulcer was not responding to empirical antimicrobial therapy. A real-time polymerase chain reaction from an aqueous aspirate of the right eye detected 422 copies of M. tuberculosis. Subsequent investigations revealed positive Mantoux and interferon-gamma release assay, supportive radiology. The patient was successfully treated with a course of antitubercular therapy and topical steroids. Hypopyon corneal ulcer, though a rare manifestation of ocular tuberculosis, should be considered in cases not responding to standard antimicrobial therapy.http://www.ijo.in/article.asp?issn=0301-4738;year=2020;volume=68;issue=5;spage=922;epage=924;aulast=antituberculosis therapycorneal ulcerhypopyonocular tuberculosistuberculosisuveitis |
| spellingShingle | Neethu Latiff Meena Lakshmipathy M K Janani Parthopratim Dutta Majumder Tuberculous corneal ulcer with hypopyon: A case report Indian Journal of Ophthalmology antituberculosis therapy corneal ulcer hypopyon ocular tuberculosis tuberculosis uveitis |
| title | Tuberculous corneal ulcer with hypopyon: A case report |
| title_full | Tuberculous corneal ulcer with hypopyon: A case report |
| title_fullStr | Tuberculous corneal ulcer with hypopyon: A case report |
| title_full_unstemmed | Tuberculous corneal ulcer with hypopyon: A case report |
| title_short | Tuberculous corneal ulcer with hypopyon: A case report |
| title_sort | tuberculous corneal ulcer with hypopyon a case report |
| topic | antituberculosis therapy corneal ulcer hypopyon ocular tuberculosis tuberculosis uveitis |
| url | http://www.ijo.in/article.asp?issn=0301-4738;year=2020;volume=68;issue=5;spage=922;epage=924;aulast= |
| work_keys_str_mv | AT neethulatiff tuberculouscornealulcerwithhypopyonacasereport AT meenalakshmipathy tuberculouscornealulcerwithhypopyonacasereport AT mkjanani tuberculouscornealulcerwithhypopyonacasereport AT parthopratimduttamajumder tuberculouscornealulcerwithhypopyonacasereport |