Water-stable perovskite-loaded nanogels containing antioxidant property for highly sensitive and selective detection of roxithromycin in animal-derived food products
Abstract Luminescent inorganic lead halide perovskite nanoparticles lack stability in aqueous solutions, limiting their application to optical sensors. Here, hybrid CsPbBr3-loaded MIP nanogels were developed with enhanced stability in aqueous media. Multifunctional MIP nanogels with antioxidant func...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-02-01
|
| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-022-07030-9 |
| _version_ | 1818501304973000704 |
|---|---|
| author | Jinsol Han Mirkomil Sharipov Soojin Hwang Youngil Lee Bui The Huy Yong-Ill Lee |
| author_facet | Jinsol Han Mirkomil Sharipov Soojin Hwang Youngil Lee Bui The Huy Yong-Ill Lee |
| author_sort | Jinsol Han |
| collection | DOAJ |
| description | Abstract Luminescent inorganic lead halide perovskite nanoparticles lack stability in aqueous solutions, limiting their application to optical sensors. Here, hybrid CsPbBr3-loaded MIP nanogels were developed with enhanced stability in aqueous media. Multifunctional MIP nanogels with antioxidant function and hydrophobic cavities were synthesized from HEMA derivatives in the presence of roxithromycin as a template. The CsPbBr3 nanoparticles were loaded into pre-synthesized MIP nanogels via in-situ synthesis with a size distribution of 200 nm. The developed CsPbBr3-nanogel exhibits excellent stability to air/moisture and enhanced stability toward an aqueous solvent. The developed CsPbBr3-loaded MIP nanogels showed a selective and sensitive detection of ROX with a limit of detection calculated to be 1.7 × 10–5 μg/mL (20.6 pM). The developed CsPbBr3-loaded MIP antioxidant-nanogels were evaluated on practical application for the quantitative determination of ROX antibiotic in animal-derived food products with excellent analytical performance. The detection of ROX in animal-derived food products showed good recovery results, making them an ideal candidate for sensing ROX. |
| first_indexed | 2024-12-10T20:54:20Z |
| format | Article |
| id | doaj.art-d3ed6cc0fd3f4570b241a1ba2940ccfa |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-12-10T20:54:20Z |
| publishDate | 2022-02-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-d3ed6cc0fd3f4570b241a1ba2940ccfa2022-12-22T01:34:01ZengNature PortfolioScientific Reports2045-23222022-02-0112111110.1038/s41598-022-07030-9Water-stable perovskite-loaded nanogels containing antioxidant property for highly sensitive and selective detection of roxithromycin in animal-derived food productsJinsol Han0Mirkomil Sharipov1Soojin Hwang2Youngil Lee3Bui The Huy4Yong-Ill Lee5Department of Materials Convergence and System Enginering, Changwon National UniversityDepartment of Materials Convergence and System Enginering, Changwon National UniversityDepartment of Materials Convergence and System Enginering, Changwon National UniversityDepartment of Chemistry, University of UlsanDepartment of Materials Convergence and System Enginering, Changwon National UniversityDepartment of Materials Convergence and System Enginering, Changwon National UniversityAbstract Luminescent inorganic lead halide perovskite nanoparticles lack stability in aqueous solutions, limiting their application to optical sensors. Here, hybrid CsPbBr3-loaded MIP nanogels were developed with enhanced stability in aqueous media. Multifunctional MIP nanogels with antioxidant function and hydrophobic cavities were synthesized from HEMA derivatives in the presence of roxithromycin as a template. The CsPbBr3 nanoparticles were loaded into pre-synthesized MIP nanogels via in-situ synthesis with a size distribution of 200 nm. The developed CsPbBr3-nanogel exhibits excellent stability to air/moisture and enhanced stability toward an aqueous solvent. The developed CsPbBr3-loaded MIP nanogels showed a selective and sensitive detection of ROX with a limit of detection calculated to be 1.7 × 10–5 μg/mL (20.6 pM). The developed CsPbBr3-loaded MIP antioxidant-nanogels were evaluated on practical application for the quantitative determination of ROX antibiotic in animal-derived food products with excellent analytical performance. The detection of ROX in animal-derived food products showed good recovery results, making them an ideal candidate for sensing ROX.https://doi.org/10.1038/s41598-022-07030-9 |
| spellingShingle | Jinsol Han Mirkomil Sharipov Soojin Hwang Youngil Lee Bui The Huy Yong-Ill Lee Water-stable perovskite-loaded nanogels containing antioxidant property for highly sensitive and selective detection of roxithromycin in animal-derived food products Scientific Reports |
| title | Water-stable perovskite-loaded nanogels containing antioxidant property for highly sensitive and selective detection of roxithromycin in animal-derived food products |
| title_full | Water-stable perovskite-loaded nanogels containing antioxidant property for highly sensitive and selective detection of roxithromycin in animal-derived food products |
| title_fullStr | Water-stable perovskite-loaded nanogels containing antioxidant property for highly sensitive and selective detection of roxithromycin in animal-derived food products |
| title_full_unstemmed | Water-stable perovskite-loaded nanogels containing antioxidant property for highly sensitive and selective detection of roxithromycin in animal-derived food products |
| title_short | Water-stable perovskite-loaded nanogels containing antioxidant property for highly sensitive and selective detection of roxithromycin in animal-derived food products |
| title_sort | water stable perovskite loaded nanogels containing antioxidant property for highly sensitive and selective detection of roxithromycin in animal derived food products |
| url | https://doi.org/10.1038/s41598-022-07030-9 |
| work_keys_str_mv | AT jinsolhan waterstableperovskiteloadednanogelscontainingantioxidantpropertyforhighlysensitiveandselectivedetectionofroxithromycininanimalderivedfoodproducts AT mirkomilsharipov waterstableperovskiteloadednanogelscontainingantioxidantpropertyforhighlysensitiveandselectivedetectionofroxithromycininanimalderivedfoodproducts AT soojinhwang waterstableperovskiteloadednanogelscontainingantioxidantpropertyforhighlysensitiveandselectivedetectionofroxithromycininanimalderivedfoodproducts AT youngillee waterstableperovskiteloadednanogelscontainingantioxidantpropertyforhighlysensitiveandselectivedetectionofroxithromycininanimalderivedfoodproducts AT buithehuy waterstableperovskiteloadednanogelscontainingantioxidantpropertyforhighlysensitiveandselectivedetectionofroxithromycininanimalderivedfoodproducts AT yongilllee waterstableperovskiteloadednanogelscontainingantioxidantpropertyforhighlysensitiveandselectivedetectionofroxithromycininanimalderivedfoodproducts |