Atypical chronic inflammatory demyelinating polyradiculoneuropathy with ophthalmoplegia and anti-sulfatide IgM positivity
Background Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is a heterogeneous group of chronic immune-mediated polyradiculoneuropathies. The clinical presentation of CIDP is mainly characterized by a classic peripheral demyelinating sensory-motor type and persists for a minimum of 2...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2023-10-01
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| Series: | Journal of International Medical Research |
| Online Access: | https://doi.org/10.1177/03000605231193575 |
| _version_ | 1797663093068660736 |
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| author | Li Chen Yanjun Zhang Nan Qin Ranran Han Yuwang Li |
| author_facet | Li Chen Yanjun Zhang Nan Qin Ranran Han Yuwang Li |
| author_sort | Li Chen |
| collection | DOAJ |
| description | Background Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is a heterogeneous group of chronic immune-mediated polyradiculoneuropathies. The clinical presentation of CIDP is mainly characterized by a classic peripheral demyelinating sensory-motor type and persists for a minimum of 2 months. However, CIDP may also present with atypical symptoms. Case presentation: This report presents the case of a patient with CIDP with ophthalmoplegia and anti-sulfatide IgM antibodies. Maintenance intravenous immunoglobulin and glucocorticoid therapies were administered to the patient in accordance with the clinical, laboratory, and electrophysiological findings, which were indicative of CIDP. The treatment partially improved the symptoms, and no recurrence was detected throughout the 3-month monitoring phase. Conclusions This study combines a retrospective analysis and a literature review to explore the possible mechanism of CIDP. |
| first_indexed | 2024-03-11T19:08:38Z |
| format | Article |
| id | doaj.art-d3ee4ee52c3742caa6a71922b54b6811 |
| institution | Directory Open Access Journal |
| issn | 1473-2300 |
| language | English |
| last_indexed | 2024-03-11T19:08:38Z |
| publishDate | 2023-10-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Journal of International Medical Research |
| spelling | doaj.art-d3ee4ee52c3742caa6a71922b54b68112023-10-10T01:03:32ZengSAGE PublishingJournal of International Medical Research1473-23002023-10-015110.1177/03000605231193575Atypical chronic inflammatory demyelinating polyradiculoneuropathy with ophthalmoplegia and anti-sulfatide IgM positivityLi ChenYanjun ZhangNan QinRanran HanYuwang LiBackground Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is a heterogeneous group of chronic immune-mediated polyradiculoneuropathies. The clinical presentation of CIDP is mainly characterized by a classic peripheral demyelinating sensory-motor type and persists for a minimum of 2 months. However, CIDP may also present with atypical symptoms. Case presentation: This report presents the case of a patient with CIDP with ophthalmoplegia and anti-sulfatide IgM antibodies. Maintenance intravenous immunoglobulin and glucocorticoid therapies were administered to the patient in accordance with the clinical, laboratory, and electrophysiological findings, which were indicative of CIDP. The treatment partially improved the symptoms, and no recurrence was detected throughout the 3-month monitoring phase. Conclusions This study combines a retrospective analysis and a literature review to explore the possible mechanism of CIDP.https://doi.org/10.1177/03000605231193575 |
| spellingShingle | Li Chen Yanjun Zhang Nan Qin Ranran Han Yuwang Li Atypical chronic inflammatory demyelinating polyradiculoneuropathy with ophthalmoplegia and anti-sulfatide IgM positivity Journal of International Medical Research |
| title | Atypical chronic inflammatory demyelinating polyradiculoneuropathy with ophthalmoplegia and anti-sulfatide IgM positivity |
| title_full | Atypical chronic inflammatory demyelinating polyradiculoneuropathy with ophthalmoplegia and anti-sulfatide IgM positivity |
| title_fullStr | Atypical chronic inflammatory demyelinating polyradiculoneuropathy with ophthalmoplegia and anti-sulfatide IgM positivity |
| title_full_unstemmed | Atypical chronic inflammatory demyelinating polyradiculoneuropathy with ophthalmoplegia and anti-sulfatide IgM positivity |
| title_short | Atypical chronic inflammatory demyelinating polyradiculoneuropathy with ophthalmoplegia and anti-sulfatide IgM positivity |
| title_sort | atypical chronic inflammatory demyelinating polyradiculoneuropathy with ophthalmoplegia and anti sulfatide igm positivity |
| url | https://doi.org/10.1177/03000605231193575 |
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