A coinfection of severe leptospirosis and scrub typhus in Indian Himalayas
Scrub typhus and leptospirosis are zoonosis and systemic febrile illnesses with diverse, nonspecific clinical manifestations, and shared risk factors for coinfection. Diagnosis of the coinfection is dependent on laboratory serological tests, which are under used. A coinfection from Uttarakhand Himal...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2019-01-01
|
| Series: | Journal of Family Medicine and Primary Care |
| Subjects: | |
| Online Access: | http://www.jfmpc.com/article.asp?issn=2249-4863;year=2019;volume=8;issue=10;spage=3416;epage=3418;aulast=Mehta |
| _version_ | 1817985264593666048 |
|---|---|
| author | Vibha Mehta Ankith Bhasi Prasan Kumar Panda Pratima Gupta |
| author_facet | Vibha Mehta Ankith Bhasi Prasan Kumar Panda Pratima Gupta |
| author_sort | Vibha Mehta |
| collection | DOAJ |
| description | Scrub typhus and leptospirosis are zoonosis and systemic febrile illnesses with diverse, nonspecific clinical manifestations, and shared risk factors for coinfection. Diagnosis of the coinfection is dependent on laboratory serological tests, which are under used. A coinfection from Uttarakhand Himalayan region is not yet reported. A 25-year-old man from altitude of 2126 feet above sea level presented with fever, myalgia, jaundice, oliguria, mental confusion, and tender hepatomegaly. Investigations revealed leukocytosis, thrombocytopenia, impaired liver function tests, renal dysfunction with neurological involvement. Leptospira immunoglobulin IgM enzyme linked immunosorbent assay (ELISA) and scrub typhus immunochromatography test were positive. This coinfection is first to be documented in this holy Indian Himalayas. Clinical suspicion, early laboratory diagnosis, and early treatment could prevent complications and fatal outcomes. Coinfection of this type may be considered when there is persistence of fever and a treatment response to doxycycline. |
| first_indexed | 2024-04-13T23:56:02Z |
| format | Article |
| id | doaj.art-d3efbb3578084dac97865e67ebc8e497 |
| institution | Directory Open Access Journal |
| issn | 2249-4863 |
| language | English |
| last_indexed | 2024-04-13T23:56:02Z |
| publishDate | 2019-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Family Medicine and Primary Care |
| spelling | doaj.art-d3efbb3578084dac97865e67ebc8e4972022-12-22T02:23:54ZengWolters Kluwer Medknow PublicationsJournal of Family Medicine and Primary Care2249-48632019-01-018103416341810.4103/jfmpc.jfmpc_614_19A coinfection of severe leptospirosis and scrub typhus in Indian HimalayasVibha MehtaAnkith BhasiPrasan Kumar PandaPratima GuptaScrub typhus and leptospirosis are zoonosis and systemic febrile illnesses with diverse, nonspecific clinical manifestations, and shared risk factors for coinfection. Diagnosis of the coinfection is dependent on laboratory serological tests, which are under used. A coinfection from Uttarakhand Himalayan region is not yet reported. A 25-year-old man from altitude of 2126 feet above sea level presented with fever, myalgia, jaundice, oliguria, mental confusion, and tender hepatomegaly. Investigations revealed leukocytosis, thrombocytopenia, impaired liver function tests, renal dysfunction with neurological involvement. Leptospira immunoglobulin IgM enzyme linked immunosorbent assay (ELISA) and scrub typhus immunochromatography test were positive. This coinfection is first to be documented in this holy Indian Himalayas. Clinical suspicion, early laboratory diagnosis, and early treatment could prevent complications and fatal outcomes. Coinfection of this type may be considered when there is persistence of fever and a treatment response to doxycycline.http://www.jfmpc.com/article.asp?issn=2249-4863;year=2019;volume=8;issue=10;spage=3416;epage=3418;aulast=Mehtaacute febrile illnessprimary carerickettsiosisserologyspirochaetosiszoonosis |
| spellingShingle | Vibha Mehta Ankith Bhasi Prasan Kumar Panda Pratima Gupta A coinfection of severe leptospirosis and scrub typhus in Indian Himalayas Journal of Family Medicine and Primary Care acute febrile illness primary care rickettsiosis serology spirochaetosis zoonosis |
| title | A coinfection of severe leptospirosis and scrub typhus in Indian Himalayas |
| title_full | A coinfection of severe leptospirosis and scrub typhus in Indian Himalayas |
| title_fullStr | A coinfection of severe leptospirosis and scrub typhus in Indian Himalayas |
| title_full_unstemmed | A coinfection of severe leptospirosis and scrub typhus in Indian Himalayas |
| title_short | A coinfection of severe leptospirosis and scrub typhus in Indian Himalayas |
| title_sort | coinfection of severe leptospirosis and scrub typhus in indian himalayas |
| topic | acute febrile illness primary care rickettsiosis serology spirochaetosis zoonosis |
| url | http://www.jfmpc.com/article.asp?issn=2249-4863;year=2019;volume=8;issue=10;spage=3416;epage=3418;aulast=Mehta |
| work_keys_str_mv | AT vibhamehta acoinfectionofsevereleptospirosisandscrubtyphusinindianhimalayas AT ankithbhasi acoinfectionofsevereleptospirosisandscrubtyphusinindianhimalayas AT prasankumarpanda acoinfectionofsevereleptospirosisandscrubtyphusinindianhimalayas AT pratimagupta acoinfectionofsevereleptospirosisandscrubtyphusinindianhimalayas AT vibhamehta coinfectionofsevereleptospirosisandscrubtyphusinindianhimalayas AT ankithbhasi coinfectionofsevereleptospirosisandscrubtyphusinindianhimalayas AT prasankumarpanda coinfectionofsevereleptospirosisandscrubtyphusinindianhimalayas AT pratimagupta coinfectionofsevereleptospirosisandscrubtyphusinindianhimalayas |