Osmolar Modulation Drives Reversible Cell Cycle Exit and Human Pluripotent Cell Differentiation via NF‐κВ and WNT Signaling

Osmolar Modulation Drives Reversible Cell Cycle Exit and Human Pluripotent Cell Differentiation via NF‐κВ and WNT Signaling

Abstract Terminally differentiated cells are commonly regarded as the most stable cell state in adult organisms, characterized by growth arrest while fulfilling their specialized functions. A better understanding of the mechanisms involved in promoting cell cycle exit will improve the ability to dif...

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Bibliographic Details
Main Authors: Jonathan Sai‐Hong Chui, Teresa Izuel‐Idoype, Alessandra Qualizza, Rita Pires deAlmeida, Lindsey Piessens, Bernard K. van derVeer, Gert Vanmarcke, Aneta Malesa, Paraskevi Athanasouli, Ruben Boon, Joris Vriens, Leo vanGrunsven, Kian Peng Koh, Catherine M. Verfaillie, Frederic Lluis
Format: Article
Language:English
Published: Wiley 2024-02-01
Series:Advanced Science
Subjects:
hepatic model
stem cell differentiation
cell cycle
WNT signaling
NF‐kB signaling
Online Access:https://doi.org/10.1002/advs.202307554

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