Case report: Acinetobacter baumannii septic arthritis in an immunocompetent infant
Acinetobacter baumannii is a gram-negative coccobacilli, mainly causing nosocomial infections with poor prognosis, especially in patients with prolonged hospitalization or antibiotics administration. A. baumannii pneumonia is the most common clinical form and usually occurs in critically ill patient...
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Frontiers Media S.A.
2023-03-01
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| Series: | Frontiers in Medicine |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fmed.2023.1135178/full |
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| author | Yi Liao Jiapeng Xiao Feng Fang Hua Zhou Lingling Liu Xinglou Liu |
| author_facet | Yi Liao Jiapeng Xiao Feng Fang Hua Zhou Lingling Liu Xinglou Liu |
| author_sort | Yi Liao |
| collection | DOAJ |
| description | Acinetobacter baumannii is a gram-negative coccobacilli, mainly causing nosocomial infections with poor prognosis, especially in patients with prolonged hospitalization or antibiotics administration. A. baumannii pneumonia is the most common clinical form and usually occurs in critically ill patients in the intensive care unit. However, septic arthritis caused by A. baumannii is rarely reported. In this report, we describe a case of A. baumannii septic arthritis combined with incomplete Kawasaki disease in an infant. The child's chief complaint was a 2-week intermittent fever with poor response to antibiotics. Initial physical examination revealed swollen lymph nodes in the neck, pharynx congestion, and the appearance of rashes. Combined with laboratory tests, the diagnosis of incomplete Kawasaki disease was considered. After administration of high-dose intravenous immunoglobulin and corticosteroids, the child's fever improved and periungual desquamation appeared simultaneously. Swelling of the right knee occurred 5 days after the fever improved and imaging tests of MRI and ultrasound suggested the existence of infection. A diagnosis of septic arthritis was established subsequently, and arthroscopy was carried out. A. baumannii was finally identified by metagenomics next-generation sequencing of joint draining fluid for pathogenic microorganisms. Treatment with meropenem was then started. The patient eventually recovered and was discharged from the hospital after 23 days of treatment with meropenem. Although A. baumannii is not a common bacterium of septic arthritis, this rare infection can still occur in infants. Early diagnosis, pathogenic identification, and target antibiotic treatment are important to reduce the occurrence of joint sequelae. |
| first_indexed | 2024-04-10T06:32:19Z |
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| id | doaj.art-d3f6fcd1858b452b9744f2bee4ea1250 |
| institution | Directory Open Access Journal |
| issn | 2296-858X |
| language | English |
| last_indexed | 2024-04-10T06:32:19Z |
| publishDate | 2023-03-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Medicine |
| spelling | doaj.art-d3f6fcd1858b452b9744f2bee4ea12502023-03-01T06:33:02ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2023-03-011010.3389/fmed.2023.11351781135178Case report: Acinetobacter baumannii septic arthritis in an immunocompetent infantYi Liao0Jiapeng Xiao1Feng Fang2Hua Zhou3Lingling Liu4Xinglou Liu5Department of Pediatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, ChinaDepartment of Pediatrics, Luotian County People's Hospital, Huanggang, ChinaDepartment of Pediatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, ChinaDepartment of Pediatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, ChinaDepartment of Pediatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, ChinaDepartment of Pediatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, ChinaAcinetobacter baumannii is a gram-negative coccobacilli, mainly causing nosocomial infections with poor prognosis, especially in patients with prolonged hospitalization or antibiotics administration. A. baumannii pneumonia is the most common clinical form and usually occurs in critically ill patients in the intensive care unit. However, septic arthritis caused by A. baumannii is rarely reported. In this report, we describe a case of A. baumannii septic arthritis combined with incomplete Kawasaki disease in an infant. The child's chief complaint was a 2-week intermittent fever with poor response to antibiotics. Initial physical examination revealed swollen lymph nodes in the neck, pharynx congestion, and the appearance of rashes. Combined with laboratory tests, the diagnosis of incomplete Kawasaki disease was considered. After administration of high-dose intravenous immunoglobulin and corticosteroids, the child's fever improved and periungual desquamation appeared simultaneously. Swelling of the right knee occurred 5 days after the fever improved and imaging tests of MRI and ultrasound suggested the existence of infection. A diagnosis of septic arthritis was established subsequently, and arthroscopy was carried out. A. baumannii was finally identified by metagenomics next-generation sequencing of joint draining fluid for pathogenic microorganisms. Treatment with meropenem was then started. The patient eventually recovered and was discharged from the hospital after 23 days of treatment with meropenem. Although A. baumannii is not a common bacterium of septic arthritis, this rare infection can still occur in infants. Early diagnosis, pathogenic identification, and target antibiotic treatment are important to reduce the occurrence of joint sequelae.https://www.frontiersin.org/articles/10.3389/fmed.2023.1135178/fullAcinetobacter baumanniiseptic arthritisinfantmetagenomics next-generation sequencingcase report |
| spellingShingle | Yi Liao Jiapeng Xiao Feng Fang Hua Zhou Lingling Liu Xinglou Liu Case report: Acinetobacter baumannii septic arthritis in an immunocompetent infant Frontiers in Medicine Acinetobacter baumannii septic arthritis infant metagenomics next-generation sequencing case report |
| title | Case report: Acinetobacter baumannii septic arthritis in an immunocompetent infant |
| title_full | Case report: Acinetobacter baumannii septic arthritis in an immunocompetent infant |
| title_fullStr | Case report: Acinetobacter baumannii septic arthritis in an immunocompetent infant |
| title_full_unstemmed | Case report: Acinetobacter baumannii septic arthritis in an immunocompetent infant |
| title_short | Case report: Acinetobacter baumannii septic arthritis in an immunocompetent infant |
| title_sort | case report acinetobacter baumannii septic arthritis in an immunocompetent infant |
| topic | Acinetobacter baumannii septic arthritis infant metagenomics next-generation sequencing case report |
| url | https://www.frontiersin.org/articles/10.3389/fmed.2023.1135178/full |
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