Aggressive central giant cell granuloma of the mandible, a diagnostic dilemma

Central giant cell granuloma (CGCG) of the jaw bones is a rare benign intraosseous lesions that is commonly seen as indolent lesions in the mandible anterior to the first molar. It is a localized osteolytic lesion with the varied biologic behavior of aggression which affects the jaw bones. There is...

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Main Authors: Pavitra Baskaran, Margathavalli Gopal, Varun Rastogi, Satya Ranjan Misra
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2015-01-01
Series:Journal of Oral and Maxillofacial Radiology
Subjects:
Online Access:http://www.joomr.org/article.asp?issn=2321-3841;year=2015;volume=3;issue=3;spage=88;epage=91;aulast=Baskaran
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author Pavitra Baskaran
Margathavalli Gopal
Varun Rastogi
Satya Ranjan Misra
author_facet Pavitra Baskaran
Margathavalli Gopal
Varun Rastogi
Satya Ranjan Misra
author_sort Pavitra Baskaran
collection DOAJ
description Central giant cell granuloma (CGCG) of the jaw bones is a rare benign intraosseous lesions that is commonly seen as indolent lesions in the mandible anterior to the first molar. It is a localized osteolytic lesion with the varied biologic behavior of aggression which affects the jaw bones. There is much controversy regarding it arising as a result of trauma and its connection with the giant cell lesion seen in the long bones. Since the lesion is uncommon, does not possess any characteristic clinical or radiologic features, and resembles neoplasms, the diagnosis is initially some odontogenic or non-odontogenic neoplasm till a definitive histologic diagnosis of CGCG is made. CGCG is divided into a rare aggressive variant and a common nonaggressive variant based on the clinical and radiographic features. The present case is a rare aggressive CGCG seen in the posterior mandible associated with mandibular swelling, rapid growth, pain, paraesthesia, and cortical bone perforation.
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spelling doaj.art-d3f8500664d14d7db4e607ff9fb216e32022-12-21T19:25:34ZengWolters Kluwer Medknow PublicationsJournal of Oral and Maxillofacial Radiology2321-385X2015-01-0133889110.4103/2321-3841.170614Aggressive central giant cell granuloma of the mandible, a diagnostic dilemmaPavitra BaskaranMargathavalli GopalVarun RastogiSatya Ranjan MisraCentral giant cell granuloma (CGCG) of the jaw bones is a rare benign intraosseous lesions that is commonly seen as indolent lesions in the mandible anterior to the first molar. It is a localized osteolytic lesion with the varied biologic behavior of aggression which affects the jaw bones. There is much controversy regarding it arising as a result of trauma and its connection with the giant cell lesion seen in the long bones. Since the lesion is uncommon, does not possess any characteristic clinical or radiologic features, and resembles neoplasms, the diagnosis is initially some odontogenic or non-odontogenic neoplasm till a definitive histologic diagnosis of CGCG is made. CGCG is divided into a rare aggressive variant and a common nonaggressive variant based on the clinical and radiographic features. The present case is a rare aggressive CGCG seen in the posterior mandible associated with mandibular swelling, rapid growth, pain, paraesthesia, and cortical bone perforation.http://www.joomr.org/article.asp?issn=2321-3841;year=2015;volume=3;issue=3;spage=88;epage=91;aulast=BaskaranAggressive jaw lesiongiant cell lesionhistopathologic diagnosismultilocular radiolucency
spellingShingle Pavitra Baskaran
Margathavalli Gopal
Varun Rastogi
Satya Ranjan Misra
Aggressive central giant cell granuloma of the mandible, a diagnostic dilemma
Journal of Oral and Maxillofacial Radiology
Aggressive jaw lesion
giant cell lesion
histopathologic diagnosis
multilocular radiolucency
title Aggressive central giant cell granuloma of the mandible, a diagnostic dilemma
title_full Aggressive central giant cell granuloma of the mandible, a diagnostic dilemma
title_fullStr Aggressive central giant cell granuloma of the mandible, a diagnostic dilemma
title_full_unstemmed Aggressive central giant cell granuloma of the mandible, a diagnostic dilemma
title_short Aggressive central giant cell granuloma of the mandible, a diagnostic dilemma
title_sort aggressive central giant cell granuloma of the mandible a diagnostic dilemma
topic Aggressive jaw lesion
giant cell lesion
histopathologic diagnosis
multilocular radiolucency
url http://www.joomr.org/article.asp?issn=2321-3841;year=2015;volume=3;issue=3;spage=88;epage=91;aulast=Baskaran
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AT margathavalligopal aggressivecentralgiantcellgranulomaofthemandibleadiagnosticdilemma
AT varunrastogi aggressivecentralgiantcellgranulomaofthemandibleadiagnosticdilemma
AT satyaranjanmisra aggressivecentralgiantcellgranulomaofthemandibleadiagnosticdilemma