Risk stratification and pathway analysis based on graph neural network and interpretable algorithm

Risk stratification and pathway analysis based on graph neural network and interpretable algorithm

Abstract Background Pathway-based analysis of transcriptomic data has shown greater stability and better performance than traditional gene-based analysis. Until now, some pathway-based deep learning models have been developed for bioinformatic analysis, but these models have not fully considered the...

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Bibliographic Details
Main Authors: Bilin Liang, Haifan Gong, Lu Lu, Jie Xu
Format: Article
Language:English
Published: BMC 2022-09-01
Series:BMC Bioinformatics
Subjects:
Graph neural network
Deep learning
Risk classification
Pathway
Interpretability
Online Access:https://doi.org/10.1186/s12859-022-04950-1

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