A fine mapping of single nucleotide variants and haplotype analysis of IL13 gene in patients with Leishmania guyanensis-cutaneous leishmaniasis and plasma cytokines IL-4, IL-5, and IL-13

A fine mapping of single nucleotide variants and haplotype analysis of IL13 gene in patients with Leishmania guyanensis-cutaneous leishmaniasis and plasma cytokines IL-4, IL-5, and IL-13

IntroductionLeishmaniasis continues to pose a substantial health burden in 97 countries worldwide. The progression and outcome of Leishmania infection are influenced by various factors, including the cytokine milieu, the skin microbiota at the infection site, the specific Leishmania species involved...

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Main Authors: José do Espírito Santo Junior, Josué Lacerda de Souza, Lener Santos da Silva, Cilana Chagas da Silva, Tuanny Arruda do Nascimento, Mara Lúcia Gomes de Souza, Alyne Farias da Cunha, Jacqueline da Silva Batista, José Pereira de Moura Neto, Marcus Vinitius de Farias Guerra, Rajendranath Ramasawmy
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Immunology
Subjects:
Leishmania guyanensis
IL-13
single nucleotide variants
cutaneous leishmaniasis
susceptibility
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1232488/full

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