Successful Penile Replantation and the Role of Postreplantation Sildenafil Therapy: Report of 2 Cases and Literature Review
Penile amputation is a rare clinical emergency necessitating urgent urologic and microsurgical intervention. Microvascular replantation has become a conventional form of management, associated with significantly increased viability of the implanted tissue and a lower rate of complications. However,...
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Format: | Article |
Language: | English |
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Oxford University Press
2019-09-01
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Series: | Sexual Medicine |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2050116119300455 |
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author | Shibo Fu, PhD Dachao Zheng, MM Minkai Xie, PhD Haijun Yao, MM Zhong Wang, PhD, MD |
author_facet | Shibo Fu, PhD Dachao Zheng, MM Minkai Xie, PhD Haijun Yao, MM Zhong Wang, PhD, MD |
author_sort | Shibo Fu, PhD |
collection | DOAJ |
description | Penile amputation is a rare clinical emergency necessitating urgent urologic and microsurgical intervention. Microvascular replantation has become a conventional form of management, associated with significantly increased viability of the implanted tissue and a lower rate of complications. However, postreplantation treatment intended to promote early recovery of sexual function has been reported only seldomly. Here we report 2 cases of successful penile replantation with postreplantation daily sildenafil therapy. The patients were followed for 24 months and 8 months, respectively, from the date of repair. First intercourse was achieved at 92 days and 105 days, respectively. This is the first report of the use of phosphodiesterase type 5 inhibitors in postoperative care of penile replantation.Fu S, Zheng D, Xie M, et al. Successful Penile Replantation and the Role of Postreplantation Sildenafil Therapy: Report of 2 Cases and Literature Review. Sex Med 2019;7:352–356. Key Words: Penile Amputation, Penile Replantation, Sildenafil, Erectile Function recovery |
first_indexed | 2024-03-12T10:59:57Z |
format | Article |
id | doaj.art-d411e110527b4d5a843c23444ee64093 |
institution | Directory Open Access Journal |
issn | 2050-1161 |
language | English |
last_indexed | 2024-03-12T10:59:57Z |
publishDate | 2019-09-01 |
publisher | Oxford University Press |
record_format | Article |
series | Sexual Medicine |
spelling | doaj.art-d411e110527b4d5a843c23444ee640932023-09-02T05:51:45ZengOxford University PressSexual Medicine2050-11612019-09-0173352356Successful Penile Replantation and the Role of Postreplantation Sildenafil Therapy: Report of 2 Cases and Literature ReviewShibo Fu, PhD0Dachao Zheng, MM1Minkai Xie, PhD2Haijun Yao, MM3Zhong Wang, PhD, MD4Department of Urology and Andrology, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, ChinaDepartment of Urology and Andrology, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, ChinaDepartment of Urology and Andrology, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, ChinaDepartment of Urology and Andrology, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, ChinaCorresponding Author: Zhong Wang, PhD, MD, Department of Urology and Andrology, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, China. Tel: +86 (021) 23271699-5116; Fax: +86 (021) 23271699-1007; Department of Urology and Andrology, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, ChinaPenile amputation is a rare clinical emergency necessitating urgent urologic and microsurgical intervention. Microvascular replantation has become a conventional form of management, associated with significantly increased viability of the implanted tissue and a lower rate of complications. However, postreplantation treatment intended to promote early recovery of sexual function has been reported only seldomly. Here we report 2 cases of successful penile replantation with postreplantation daily sildenafil therapy. The patients were followed for 24 months and 8 months, respectively, from the date of repair. First intercourse was achieved at 92 days and 105 days, respectively. This is the first report of the use of phosphodiesterase type 5 inhibitors in postoperative care of penile replantation.Fu S, Zheng D, Xie M, et al. Successful Penile Replantation and the Role of Postreplantation Sildenafil Therapy: Report of 2 Cases and Literature Review. Sex Med 2019;7:352–356. Key Words: Penile Amputation, Penile Replantation, Sildenafil, Erectile Function recoveryhttp://www.sciencedirect.com/science/article/pii/S2050116119300455 |
spellingShingle | Shibo Fu, PhD Dachao Zheng, MM Minkai Xie, PhD Haijun Yao, MM Zhong Wang, PhD, MD Successful Penile Replantation and the Role of Postreplantation Sildenafil Therapy: Report of 2 Cases and Literature Review Sexual Medicine |
title | Successful Penile Replantation and the Role of Postreplantation Sildenafil Therapy: Report of 2 Cases and Literature Review |
title_full | Successful Penile Replantation and the Role of Postreplantation Sildenafil Therapy: Report of 2 Cases and Literature Review |
title_fullStr | Successful Penile Replantation and the Role of Postreplantation Sildenafil Therapy: Report of 2 Cases and Literature Review |
title_full_unstemmed | Successful Penile Replantation and the Role of Postreplantation Sildenafil Therapy: Report of 2 Cases and Literature Review |
title_short | Successful Penile Replantation and the Role of Postreplantation Sildenafil Therapy: Report of 2 Cases and Literature Review |
title_sort | successful penile replantation and the role of postreplantation sildenafil therapy report of 2 cases and literature review |
url | http://www.sciencedirect.com/science/article/pii/S2050116119300455 |
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