Successful Penile Replantation and the Role of Postreplantation Sildenafil Therapy: Report of 2 Cases and Literature Review

Penile amputation is a rare clinical emergency necessitating urgent urologic and microsurgical intervention. Microvascular replantation has become a conventional form of management, associated with significantly increased viability of the implanted tissue and a lower rate of complications. However,...

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Main Authors: Shibo Fu, PhD, Dachao Zheng, MM, Minkai Xie, PhD, Haijun Yao, MM, Zhong Wang, PhD, MD
Format: Article
Language:English
Published: Oxford University Press 2019-09-01
Series:Sexual Medicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2050116119300455
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author Shibo Fu, PhD
Dachao Zheng, MM
Minkai Xie, PhD
Haijun Yao, MM
Zhong Wang, PhD, MD
author_facet Shibo Fu, PhD
Dachao Zheng, MM
Minkai Xie, PhD
Haijun Yao, MM
Zhong Wang, PhD, MD
author_sort Shibo Fu, PhD
collection DOAJ
description Penile amputation is a rare clinical emergency necessitating urgent urologic and microsurgical intervention. Microvascular replantation has become a conventional form of management, associated with significantly increased viability of the implanted tissue and a lower rate of complications. However, postreplantation treatment intended to promote early recovery of sexual function has been reported only seldomly. Here we report 2 cases of successful penile replantation with postreplantation daily sildenafil therapy. The patients were followed for 24 months and 8 months, respectively, from the date of repair. First intercourse was achieved at 92 days and 105 days, respectively. This is the first report of the use of phosphodiesterase type 5 inhibitors in postoperative care of penile replantation.Fu S, Zheng D, Xie M, et al. Successful Penile Replantation and the Role of Postreplantation Sildenafil Therapy: Report of 2 Cases and Literature Review. Sex Med 2019;7:352–356. Key Words: Penile Amputation, Penile Replantation, Sildenafil, Erectile Function recovery
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spelling doaj.art-d411e110527b4d5a843c23444ee640932023-09-02T05:51:45ZengOxford University PressSexual Medicine2050-11612019-09-0173352356Successful Penile Replantation and the Role of Postreplantation Sildenafil Therapy: Report of 2 Cases and Literature ReviewShibo Fu, PhD0Dachao Zheng, MM1Minkai Xie, PhD2Haijun Yao, MM3Zhong Wang, PhD, MD4Department of Urology and Andrology, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, ChinaDepartment of Urology and Andrology, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, ChinaDepartment of Urology and Andrology, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, ChinaDepartment of Urology and Andrology, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, ChinaCorresponding Author: Zhong Wang, PhD, MD, Department of Urology and Andrology, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, China. Tel: +86 (021) 23271699-5116; Fax: +86 (021) 23271699-1007; Department of Urology and Andrology, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, ChinaPenile amputation is a rare clinical emergency necessitating urgent urologic and microsurgical intervention. Microvascular replantation has become a conventional form of management, associated with significantly increased viability of the implanted tissue and a lower rate of complications. However, postreplantation treatment intended to promote early recovery of sexual function has been reported only seldomly. Here we report 2 cases of successful penile replantation with postreplantation daily sildenafil therapy. The patients were followed for 24 months and 8 months, respectively, from the date of repair. First intercourse was achieved at 92 days and 105 days, respectively. This is the first report of the use of phosphodiesterase type 5 inhibitors in postoperative care of penile replantation.Fu S, Zheng D, Xie M, et al. Successful Penile Replantation and the Role of Postreplantation Sildenafil Therapy: Report of 2 Cases and Literature Review. Sex Med 2019;7:352–356. Key Words: Penile Amputation, Penile Replantation, Sildenafil, Erectile Function recoveryhttp://www.sciencedirect.com/science/article/pii/S2050116119300455
spellingShingle Shibo Fu, PhD
Dachao Zheng, MM
Minkai Xie, PhD
Haijun Yao, MM
Zhong Wang, PhD, MD
Successful Penile Replantation and the Role of Postreplantation Sildenafil Therapy: Report of 2 Cases and Literature Review
Sexual Medicine
title Successful Penile Replantation and the Role of Postreplantation Sildenafil Therapy: Report of 2 Cases and Literature Review
title_full Successful Penile Replantation and the Role of Postreplantation Sildenafil Therapy: Report of 2 Cases and Literature Review
title_fullStr Successful Penile Replantation and the Role of Postreplantation Sildenafil Therapy: Report of 2 Cases and Literature Review
title_full_unstemmed Successful Penile Replantation and the Role of Postreplantation Sildenafil Therapy: Report of 2 Cases and Literature Review
title_short Successful Penile Replantation and the Role of Postreplantation Sildenafil Therapy: Report of 2 Cases and Literature Review
title_sort successful penile replantation and the role of postreplantation sildenafil therapy report of 2 cases and literature review
url http://www.sciencedirect.com/science/article/pii/S2050116119300455
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