Targeting LSD1 in tumor immunotherapy: rationale, challenges and potential

Targeting LSD1 in tumor immunotherapy: rationale, challenges and potential

Lysine-specific demethylase 1 (LSD1) is an enzyme that removes lysine methylation marks from nucleosome histone tails and plays an important role in cancer initiation, progression, metastasis, and recurrence. Recent research shows that LSD1 regulates tumor cells and immune cells through multiple ups...

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Bibliographic Details
Main Authors:	Lei Bao, Ping Zhu, Yuan Mou, Yinhong Song, Ye Qin
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-07-01
Series:	Frontiers in Immunology
Subjects:	LSD1 immunotherapy PD-(L)1 tumor microenvironment combination therapy
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1214675/full

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