EFFECT OF INTRAVITREAL BEVACIZUMAB IN COMBINATION WITH POSTERIOR SUB-TENON TRIAMCINOLONE ON DIFFERENT LEVELS OF DIABETIC MACULAR EDEMA
Objective: To compare the efficacy of Intravitreal Bevacizumab in combination with Posterior Subtenon Triamcinolone for treatment of different levels of diabetic macular edema. Study Design: Comparative cross sectional study. Place and Duration of Study: This study was done in Retina Clinic, A...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Army Medical College Rawalpindi
2020-06-01
|
| Series: | Pakistan Armed Forces Medical Journal |
| Subjects: | |
| Online Access: | https://www.pafmj.org/index.php/PAFMJ/article/view/4607/2714 |
| _version_ | 1819012118117089280 |
|---|---|
| author | Rubab Shafqat Muhammad Kashif Habib Sara Najeeb Muhammad Usman Sadiq Aziz Jan Bashir Muhammad Irfan Sadiq |
| author_facet | Rubab Shafqat Muhammad Kashif Habib Sara Najeeb Muhammad Usman Sadiq Aziz Jan Bashir Muhammad Irfan Sadiq |
| author_sort | Rubab Shafqat |
| collection | DOAJ |
| description | Objective: To compare the efficacy of Intravitreal Bevacizumab in combination with Posterior Subtenon Triamcinolone for treatment of different levels of diabetic macular edema.
Study Design: Comparative cross sectional study.
Place and Duration of Study: This study was done in Retina Clinic, Al Shifa Trust Eye Hospital, Rawalpindi, from Jul 2017 to Dec 2017.
Methodology: Total of fifty-two patients were included in the study which were divided into two groups on the basis of foveal thickness (group 1 = Foveal Thickness <500μm, group 2 = Foveal Thickness >500μm).
Results: Both groups were treated with combination of Intra-vitreal Avastin and Posterior Subtenon Triamcinolone. The percentage decrease in foveal thickness after 6 weeks of injection in group 1 was 30.08 ± 13.035% as compared to 38.88 ± 8.883% in group 2 (p=0.006). While the improvement in BCVA in both groups after 6 weeks of injection was same (0.2 ± 0.2 in Log MAR) (p=0.521).
Conclusion: It is concluded that the use of Intravitreal Bevacizumab in combination with posterior subtenon triamcinolone for treatment of macular edema is more effective in foveal thickness >500μm as compared to thickness <500μm. |
| first_indexed | 2024-12-21T01:38:58Z |
| format | Article |
| id | doaj.art-d4143f80225a435bb91228c230b7a6cb |
| institution | Directory Open Access Journal |
| issn | 0030-9648 2411-8842 |
| language | English |
| last_indexed | 2024-12-21T01:38:58Z |
| publishDate | 2020-06-01 |
| publisher | Army Medical College Rawalpindi |
| record_format | Article |
| series | Pakistan Armed Forces Medical Journal |
| spelling | doaj.art-d4143f80225a435bb91228c230b7a6cb2022-12-21T19:20:13ZengArmy Medical College RawalpindiPakistan Armed Forces Medical Journal0030-96482411-88422020-06-01703705710EFFECT OF INTRAVITREAL BEVACIZUMAB IN COMBINATION WITH POSTERIOR SUB-TENON TRIAMCINOLONE ON DIFFERENT LEVELS OF DIABETIC MACULAR EDEMARubab Shafqat0Muhammad Kashif Habib1Sara Najeeb2Muhammad Usman Sadiq3Aziz Jan Bashir4Muhammad Irfan Sadiq5Al Shifa Eye Hospital, Rawalpindi PakistanAl Shifa Eye Hospital, Rawalpindi PakistanMohi-Ud-Din Islamic Medical College, Mirpur PakistanMohi-Ud-Din Islamic Medical College, Mirpur PakistanAl Shifa Eye Hospital, Rawalpindi PakistanM. Islam Medical & Dental College, Gujranwala PakistanObjective: To compare the efficacy of Intravitreal Bevacizumab in combination with Posterior Subtenon Triamcinolone for treatment of different levels of diabetic macular edema. Study Design: Comparative cross sectional study. Place and Duration of Study: This study was done in Retina Clinic, Al Shifa Trust Eye Hospital, Rawalpindi, from Jul 2017 to Dec 2017. Methodology: Total of fifty-two patients were included in the study which were divided into two groups on the basis of foveal thickness (group 1 = Foveal Thickness <500μm, group 2 = Foveal Thickness >500μm). Results: Both groups were treated with combination of Intra-vitreal Avastin and Posterior Subtenon Triamcinolone. The percentage decrease in foveal thickness after 6 weeks of injection in group 1 was 30.08 ± 13.035% as compared to 38.88 ± 8.883% in group 2 (p=0.006). While the improvement in BCVA in both groups after 6 weeks of injection was same (0.2 ± 0.2 in Log MAR) (p=0.521). Conclusion: It is concluded that the use of Intravitreal Bevacizumab in combination with posterior subtenon triamcinolone for treatment of macular edema is more effective in foveal thickness >500μm as compared to thickness <500μm.https://www.pafmj.org/index.php/PAFMJ/article/view/4607/2714bevacizumabmacular edemaoptical coherence tomopraphytriamcinolone acetonide |
| spellingShingle | Rubab Shafqat Muhammad Kashif Habib Sara Najeeb Muhammad Usman Sadiq Aziz Jan Bashir Muhammad Irfan Sadiq EFFECT OF INTRAVITREAL BEVACIZUMAB IN COMBINATION WITH POSTERIOR SUB-TENON TRIAMCINOLONE ON DIFFERENT LEVELS OF DIABETIC MACULAR EDEMA Pakistan Armed Forces Medical Journal bevacizumab macular edema optical coherence tomopraphy triamcinolone acetonide |
| title | EFFECT OF INTRAVITREAL BEVACIZUMAB IN COMBINATION WITH POSTERIOR SUB-TENON TRIAMCINOLONE ON DIFFERENT LEVELS OF DIABETIC MACULAR EDEMA |
| title_full | EFFECT OF INTRAVITREAL BEVACIZUMAB IN COMBINATION WITH POSTERIOR SUB-TENON TRIAMCINOLONE ON DIFFERENT LEVELS OF DIABETIC MACULAR EDEMA |
| title_fullStr | EFFECT OF INTRAVITREAL BEVACIZUMAB IN COMBINATION WITH POSTERIOR SUB-TENON TRIAMCINOLONE ON DIFFERENT LEVELS OF DIABETIC MACULAR EDEMA |
| title_full_unstemmed | EFFECT OF INTRAVITREAL BEVACIZUMAB IN COMBINATION WITH POSTERIOR SUB-TENON TRIAMCINOLONE ON DIFFERENT LEVELS OF DIABETIC MACULAR EDEMA |
| title_short | EFFECT OF INTRAVITREAL BEVACIZUMAB IN COMBINATION WITH POSTERIOR SUB-TENON TRIAMCINOLONE ON DIFFERENT LEVELS OF DIABETIC MACULAR EDEMA |
| title_sort | effect of intravitreal bevacizumab in combination with posterior sub tenon triamcinolone on different levels of diabetic macular edema |
| topic | bevacizumab macular edema optical coherence tomopraphy triamcinolone acetonide |
| url | https://www.pafmj.org/index.php/PAFMJ/article/view/4607/2714 |
| work_keys_str_mv | AT rubabshafqat effectofintravitrealbevacizumabincombinationwithposteriorsubtenontriamcinoloneondifferentlevelsofdiabeticmacularedema AT muhammadkashifhabib effectofintravitrealbevacizumabincombinationwithposteriorsubtenontriamcinoloneondifferentlevelsofdiabeticmacularedema AT saranajeeb effectofintravitrealbevacizumabincombinationwithposteriorsubtenontriamcinoloneondifferentlevelsofdiabeticmacularedema AT muhammadusmansadiq effectofintravitrealbevacizumabincombinationwithposteriorsubtenontriamcinoloneondifferentlevelsofdiabeticmacularedema AT azizjanbashir effectofintravitrealbevacizumabincombinationwithposteriorsubtenontriamcinoloneondifferentlevelsofdiabeticmacularedema AT muhammadirfansadiq effectofintravitrealbevacizumabincombinationwithposteriorsubtenontriamcinoloneondifferentlevelsofdiabeticmacularedema |