Mirizzi syndrome: The Trojan horse of gallbladder disease

Background: The incidence of Mirizzi Syndrome ranges from 0.05 to 5.7 % of patients who undergo cholecystectomy. The purpose of this study is to examine the preoperative workup and postoperative outcomes for patients diagnosed with Mirizzi Syndrome. Methods: Retrospective chart review was conducted...

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Main Authors: Mary Froehlich, MD, Elizabeth M. Sodomin, MD, Taylor Fontenot, MD, Noama Iftekhar, MD, Christian N. Chan, MD, Annabel Barber, MD
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Surgery Open Science
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589845024000253
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author Mary Froehlich, MD
Elizabeth M. Sodomin, MD
Taylor Fontenot, MD
Noama Iftekhar, MD
Christian N. Chan, MD
Annabel Barber, MD
author_facet Mary Froehlich, MD
Elizabeth M. Sodomin, MD
Taylor Fontenot, MD
Noama Iftekhar, MD
Christian N. Chan, MD
Annabel Barber, MD
author_sort Mary Froehlich, MD
collection DOAJ
description Background: The incidence of Mirizzi Syndrome ranges from 0.05 to 5.7 % of patients who undergo cholecystectomy. The purpose of this study is to examine the preoperative workup and postoperative outcomes for patients diagnosed with Mirizzi Syndrome. Methods: Retrospective chart review was conducted between January 2018 and January 2022 at a single institution. All adult patients who underwent cholecystectomy were included. Results: 1628 patients underwent cholecystectomy of which 47 were diagnosed with Mirizzi Syndrome. The majority of patients had type 1 Mirizzi Syndrome. Preoperative studies were often nondiagnostic and 81 % of cases were diagnosed intraoperatively. 66 % of cases were performed laparoscopically, an open approach was required for type V Mirizzi Syndrome. The complication rate was 25 %; most commonly a bile leak requiring ERCP. Conclusion: Mirizzi syndrome is more common than previously expected and related to patient's ability to seek timely medical care. Most cases can be completed laparoscopically however there is a high rate of complications. Key message: This study presents an additional cohort of patients found to have Mirizzi syndrome and supports the hypothesis that it is difficult to diagnose preoperatively. Cases should be attempted laparoscopically but there remains a high complication rate.
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spelling doaj.art-d414cf95bc8b486fa4353a316229dd652024-04-03T04:27:18ZengElsevierSurgery Open Science2589-84502024-03-0118103106Mirizzi syndrome: The Trojan horse of gallbladder diseaseMary Froehlich, MD0Elizabeth M. Sodomin, MD1Taylor Fontenot, MD2Noama Iftekhar, MD3Christian N. Chan, MD4Annabel Barber, MD5Corresponding author at: 1701 W Charleston Blvd, Las Vegas, NV 89102, United States of America.; Kirk Kerkorian School of Medicine at UNLV, Las Vegas, NV, United States of AmericaKirk Kerkorian School of Medicine at UNLV, Las Vegas, NV, United States of AmericaKirk Kerkorian School of Medicine at UNLV, Las Vegas, NV, United States of AmericaKirk Kerkorian School of Medicine at UNLV, Las Vegas, NV, United States of AmericaKirk Kerkorian School of Medicine at UNLV, Las Vegas, NV, United States of AmericaKirk Kerkorian School of Medicine at UNLV, Las Vegas, NV, United States of AmericaBackground: The incidence of Mirizzi Syndrome ranges from 0.05 to 5.7 % of patients who undergo cholecystectomy. The purpose of this study is to examine the preoperative workup and postoperative outcomes for patients diagnosed with Mirizzi Syndrome. Methods: Retrospective chart review was conducted between January 2018 and January 2022 at a single institution. All adult patients who underwent cholecystectomy were included. Results: 1628 patients underwent cholecystectomy of which 47 were diagnosed with Mirizzi Syndrome. The majority of patients had type 1 Mirizzi Syndrome. Preoperative studies were often nondiagnostic and 81 % of cases were diagnosed intraoperatively. 66 % of cases were performed laparoscopically, an open approach was required for type V Mirizzi Syndrome. The complication rate was 25 %; most commonly a bile leak requiring ERCP. Conclusion: Mirizzi syndrome is more common than previously expected and related to patient's ability to seek timely medical care. Most cases can be completed laparoscopically however there is a high rate of complications. Key message: This study presents an additional cohort of patients found to have Mirizzi syndrome and supports the hypothesis that it is difficult to diagnose preoperatively. Cases should be attempted laparoscopically but there remains a high complication rate.http://www.sciencedirect.com/science/article/pii/S2589845024000253Mirizzi syndromeHepatobiliarySurgical outcomesMinimally invasiveGeneral surgery
spellingShingle Mary Froehlich, MD
Elizabeth M. Sodomin, MD
Taylor Fontenot, MD
Noama Iftekhar, MD
Christian N. Chan, MD
Annabel Barber, MD
Mirizzi syndrome: The Trojan horse of gallbladder disease
Surgery Open Science
Mirizzi syndrome
Hepatobiliary
Surgical outcomes
Minimally invasive
General surgery
title Mirizzi syndrome: The Trojan horse of gallbladder disease
title_full Mirizzi syndrome: The Trojan horse of gallbladder disease
title_fullStr Mirizzi syndrome: The Trojan horse of gallbladder disease
title_full_unstemmed Mirizzi syndrome: The Trojan horse of gallbladder disease
title_short Mirizzi syndrome: The Trojan horse of gallbladder disease
title_sort mirizzi syndrome the trojan horse of gallbladder disease
topic Mirizzi syndrome
Hepatobiliary
Surgical outcomes
Minimally invasive
General surgery
url http://www.sciencedirect.com/science/article/pii/S2589845024000253
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