Proximal Tubular Expression Patterns of Megalin and Cubilin in Proteinuric Nephropathies

Proximal Tubular Expression Patterns of Megalin and Cubilin in Proteinuric Nephropathies

Receptor-mediated endocytosis is responsible for protein reabsorption in the proximal tubules. For albumin this process involves at least 2 interacting receptors, megalin and cubilin. Albumin is not usually present in the urine, indicating a highly efficient tubular reuptake under physiological cond...

Full description

Bibliographic Details
Main Authors: Jia Sun, Kjell Hultenby, Jonas Axelsson, Johan Nordström, Bing He, Annika Wernerson, Karin Lindström
Format: Article
Language:English
Published: Elsevier 2017-07-01
Series:Kidney International Reports
Subjects:
albuminuria
cubilin
megalin
proximal tubule
Online Access:http://www.sciencedirect.com/science/article/pii/S2468024917300438

Similar Items

Similar Items