Chemical composition, antimicrobial and antioxidant properties of Mentha longifolia (L.) Huds. essential oil
Introduction: Present study describes the antimicrobial activity and free radical scavenging capacity (RSC) of essential oil from Mentha longifolia (L.) Huds. Aim of this study to investigate the quality, antimicrobial and antioxidant activity of wild species Mentha longifolia essential oil from Bos...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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University of Sarajevo
2012-12-01
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| Series: | Journal of Health Sciences |
| Subjects: | |
| Online Access: | https://www.jhsci.ba/ojs/index.php/jhsci/article/view/57 |
| _version_ | 1818564306650791936 |
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| author | Haris Nikšić Elvira Kovač Bešović Elma Makarević Kemal Durić |
| author_facet | Haris Nikšić Elvira Kovač Bešović Elma Makarević Kemal Durić |
| author_sort | Haris Nikšić |
| collection | DOAJ |
| description | Introduction: Present study describes the antimicrobial activity and free radical scavenging capacity (RSC) of essential oil from Mentha longifolia (L.) Huds. Aim of this study to investigate the quality, antimicrobial and
antioxidant activity of wild species Mentha longifolia essential oil from Bosnia and Herzegovina.
Methods: The chemical profi le of essential oil was evaluated by the means of gas chromatography-mass spectrometry (GC-MS) and thin-layer chromatography (TLC). Antimicrobial activity was tested against 6
bacterial strains. RSC was assessed by measuring the scavenging activity of essential oils on 2,2- diphenyl-1-picrylhydrazil (DPPH).
Results: The main constituents of the essential oil of M. longifoliae folium were oxygenated monoterpenes,piperitone oxide (63.58%) and 1,8-cineole (12.03%). Essential oil exhibited very strong antibacterial activity.The most important antibacterial activity essential oil was expressed on Gram negative strains: Escherichia coli, Pseudomonas aerginosa and Salmonella enterica. subsp.enterica serotype ABONY. Antioxidant activity was evaluated as a RSC. Investigated essential oil was able to reduce DPPH radicals into the neutral DPPHH form (IC50=10.5 μg/ml) and this activity was dose –dependent.
Conclusion: The study revealed signifi cant antimicrobial activity of the investigated essential oil. The examined oil exhibited high RSC, which was found to be in correlation to the content of mainly monoterpene
ketones and aldehydes. These results indicate that essential oils could serve as safe antioxidant and antiseptic supplements in pharmaceuticals. |
| first_indexed | 2024-12-14T01:27:20Z |
| format | Article |
| id | doaj.art-d418b7647ece4d3088bd69621f8e2a13 |
| institution | Directory Open Access Journal |
| issn | 2232-7576 1986-8049 |
| language | English |
| last_indexed | 2024-12-14T01:27:20Z |
| publishDate | 2012-12-01 |
| publisher | University of Sarajevo |
| record_format | Article |
| series | Journal of Health Sciences |
| spelling | doaj.art-d418b7647ece4d3088bd69621f8e2a132022-12-21T23:22:08ZengUniversity of SarajevoJournal of Health Sciences2232-75761986-80492012-12-012310.17532/jhsci.2012.3857Chemical composition, antimicrobial and antioxidant properties of Mentha longifolia (L.) Huds. essential oilHaris Nikšić0Elvira Kovač Bešović1Elma Makarević2Kemal Durić3Faculty of Pharmacy University of Sarajevo, Zmaja od Bosne 8 , 71 000 Sarajevo, Bosnia and HerzegovinaFaculty of Pharmacy University of Sarajevo, Zmaja od Bosne 8 , 71 000 Sarajevo, Bosnia and HerzegovinaFaculty of Pharmacy University of Sarajevo, Zmaja od Bosne 8 , 71 000 Sarajevo, Bosnia and HerzegovinaFaculty of Pharmacy University of Sarajevo, Zmaja od Bosne 8 , 71 000 Sarajevo, Bosnia and HerzegovinaIntroduction: Present study describes the antimicrobial activity and free radical scavenging capacity (RSC) of essential oil from Mentha longifolia (L.) Huds. Aim of this study to investigate the quality, antimicrobial and antioxidant activity of wild species Mentha longifolia essential oil from Bosnia and Herzegovina. Methods: The chemical profi le of essential oil was evaluated by the means of gas chromatography-mass spectrometry (GC-MS) and thin-layer chromatography (TLC). Antimicrobial activity was tested against 6 bacterial strains. RSC was assessed by measuring the scavenging activity of essential oils on 2,2- diphenyl-1-picrylhydrazil (DPPH). Results: The main constituents of the essential oil of M. longifoliae folium were oxygenated monoterpenes,piperitone oxide (63.58%) and 1,8-cineole (12.03%). Essential oil exhibited very strong antibacterial activity.The most important antibacterial activity essential oil was expressed on Gram negative strains: Escherichia coli, Pseudomonas aerginosa and Salmonella enterica. subsp.enterica serotype ABONY. Antioxidant activity was evaluated as a RSC. Investigated essential oil was able to reduce DPPH radicals into the neutral DPPHH form (IC50=10.5 μg/ml) and this activity was dose –dependent. Conclusion: The study revealed signifi cant antimicrobial activity of the investigated essential oil. The examined oil exhibited high RSC, which was found to be in correlation to the content of mainly monoterpene ketones and aldehydes. These results indicate that essential oils could serve as safe antioxidant and antiseptic supplements in pharmaceuticals.https://www.jhsci.ba/ojs/index.php/jhsci/article/view/57Mentha longifolia (L.) Hudsessential oilchemical compositionantimicrobial activityantioxidant activity |
| spellingShingle | Haris Nikšić Elvira Kovač Bešović Elma Makarević Kemal Durić Chemical composition, antimicrobial and antioxidant properties of Mentha longifolia (L.) Huds. essential oil Journal of Health Sciences Mentha longifolia (L.) Huds essential oil chemical composition antimicrobial activity antioxidant activity |
| title | Chemical composition, antimicrobial and antioxidant properties of Mentha longifolia (L.) Huds. essential oil |
| title_full | Chemical composition, antimicrobial and antioxidant properties of Mentha longifolia (L.) Huds. essential oil |
| title_fullStr | Chemical composition, antimicrobial and antioxidant properties of Mentha longifolia (L.) Huds. essential oil |
| title_full_unstemmed | Chemical composition, antimicrobial and antioxidant properties of Mentha longifolia (L.) Huds. essential oil |
| title_short | Chemical composition, antimicrobial and antioxidant properties of Mentha longifolia (L.) Huds. essential oil |
| title_sort | chemical composition antimicrobial and antioxidant properties of mentha longifolia l huds essential oil |
| topic | Mentha longifolia (L.) Huds essential oil chemical composition antimicrobial activity antioxidant activity |
| url | https://www.jhsci.ba/ojs/index.php/jhsci/article/view/57 |
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