Association of Physical Activity and Lower Respiratory Tract Infection Outcomes in Patients With Cardiovascular Disease
Background To investigate the dose‐response association between physical activity and lower respiratory tract infection (LoRI) outcomes in patients with cardiovascular disease. Methods and Results Using the Korean National Health Insurance data, we identified individuals aged 18 to 99 years (mean ag...
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2022-03-01
|
| Series: | Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease |
| Subjects: | |
| Online Access: | https://www.ahajournals.org/doi/10.1161/JAHA.121.023775 |
| _version_ | 1797859046101876736 |
|---|---|
| author | Mi‐Hyang Jung Sang‐Wook Yi Sang Joon An Kwan‐Hyun Youn Jee‐Jeon Yi Seongwoo Han Sang‐Hyun Ihm Hae Ok Jung Ho‐Joong Youn Kyu‐Hyung Ryu |
| author_facet | Mi‐Hyang Jung Sang‐Wook Yi Sang Joon An Kwan‐Hyun Youn Jee‐Jeon Yi Seongwoo Han Sang‐Hyun Ihm Hae Ok Jung Ho‐Joong Youn Kyu‐Hyung Ryu |
| author_sort | Mi‐Hyang Jung |
| collection | DOAJ |
| description | Background To investigate the dose‐response association between physical activity and lower respiratory tract infection (LoRI) outcomes in patients with cardiovascular disease. Methods and Results Using the Korean National Health Insurance data, we identified individuals aged 18 to 99 years (mean age, 62.6±11.3 years; women, 49.6%) with cardiovascular disease who participated in health screening from January 1, 2009, to December 31, 2012 (n=1 048 502), and were followed up until 2018 for mortality and until 2019 for hospitalization. Amount of physical activity was assessed using self‐reported questionnaires and categorized into 5 groups: 0 (completely sedentary), <500, 500 to 999, 1000 to 1499, and ≥1500 metabolic equivalents of task min/wk. After controlling for various confounders, adjusted hazard ratios (95% CIs) were 1.00 (reference), 0.74 (0.70–0.78), 0.66 (0.62–0.70), 0.52 (0.47–0.57), and 0.54 (0.49–0.60) for LoRI mortality, and 1.00 (reference), 0.84 (0.83–0.85), 0.77 (0.76–0.79), 0.72 (0.70–0.73), and 0.71 (0.69–0.73) for LoRI hospitalization among those engaging in physical activity of 0, <500, 500 to 999, 1000 to 1499, and ≥1500 metabolic equivalents of task min/wk, respectively. Assuming linear association between 0 and 2000 metabolic equivalents of task min/wk, each 500–metabolic equivalents of task min/wk increase of physical activity was associated with reduced LoRI mortality and hospitalization by 22% and 13%, respectively. The negative association was stronger in the older population than in the younger population (P for interaction <0.01). Conclusions In patients with cardiovascular disease, engaging in even a low level of physical activity was associated with a decreased risk of mortality and hospitalization from LoRI than being completely sedentary, and incremental risk reduction was observed with increased physical activity. |
| first_indexed | 2024-04-09T21:23:08Z |
| format | Article |
| id | doaj.art-d41daa4143c54a8d9e744b37d8668adc |
| institution | Directory Open Access Journal |
| issn | 2047-9980 |
| language | English |
| last_indexed | 2024-04-09T21:23:08Z |
| publishDate | 2022-03-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease |
| spelling | doaj.art-d41daa4143c54a8d9e744b37d8668adc2023-03-28T04:20:50ZengWileyJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease2047-99802022-03-0111610.1161/JAHA.121.023775Association of Physical Activity and Lower Respiratory Tract Infection Outcomes in Patients With Cardiovascular DiseaseMi‐Hyang Jung0Sang‐Wook Yi1Sang Joon An2Kwan‐Hyun Youn3Jee‐Jeon Yi4Seongwoo Han5Sang‐Hyun Ihm6Hae Ok Jung7Ho‐Joong Youn8Kyu‐Hyung Ryu9Division of Cardiology, Department of Internal Medicine Seoul St. Mary’s Hospital, The Catholic University of Korea Seoul Republic of KoreaDepartment of Preventive Medicine and Public Health Catholic Kwandong University College of Medicine Gangneung Republic of KoreaDepartment of Neurology International St. Mary’s HospitalCatholic Kwandong University College of Medicine Incheon Republic of KoreaDepartment of Biomedical Art Incheon Catholic University Graduate School Incheon Republic of KoreaInstitute for Occupational and Environmental HealthCatholic Kwandong University Gangneung Republic of KoreaCardiovascular Center Dongtan Sacred Heart Hospital, Hallym University College of Medicine Hwaseong‐si Republic of KoreaDivision of Cardiology, Department of Internal Medicine Bucheon St. Mary’s Hospital, College of Medicine, The Catholic University of Korea Seoul Republic of KoreaDivision of Cardiology, Department of Internal Medicine Seoul St. Mary’s Hospital, The Catholic University of Korea Seoul Republic of KoreaDivision of Cardiology, Department of Internal Medicine Seoul St. Mary’s Hospital, The Catholic University of Korea Seoul Republic of KoreaCardiovascular Center Dongtan Sacred Heart Hospital, Hallym University College of Medicine Hwaseong‐si Republic of KoreaBackground To investigate the dose‐response association between physical activity and lower respiratory tract infection (LoRI) outcomes in patients with cardiovascular disease. Methods and Results Using the Korean National Health Insurance data, we identified individuals aged 18 to 99 years (mean age, 62.6±11.3 years; women, 49.6%) with cardiovascular disease who participated in health screening from January 1, 2009, to December 31, 2012 (n=1 048 502), and were followed up until 2018 for mortality and until 2019 for hospitalization. Amount of physical activity was assessed using self‐reported questionnaires and categorized into 5 groups: 0 (completely sedentary), <500, 500 to 999, 1000 to 1499, and ≥1500 metabolic equivalents of task min/wk. After controlling for various confounders, adjusted hazard ratios (95% CIs) were 1.00 (reference), 0.74 (0.70–0.78), 0.66 (0.62–0.70), 0.52 (0.47–0.57), and 0.54 (0.49–0.60) for LoRI mortality, and 1.00 (reference), 0.84 (0.83–0.85), 0.77 (0.76–0.79), 0.72 (0.70–0.73), and 0.71 (0.69–0.73) for LoRI hospitalization among those engaging in physical activity of 0, <500, 500 to 999, 1000 to 1499, and ≥1500 metabolic equivalents of task min/wk, respectively. Assuming linear association between 0 and 2000 metabolic equivalents of task min/wk, each 500–metabolic equivalents of task min/wk increase of physical activity was associated with reduced LoRI mortality and hospitalization by 22% and 13%, respectively. The negative association was stronger in the older population than in the younger population (P for interaction <0.01). Conclusions In patients with cardiovascular disease, engaging in even a low level of physical activity was associated with a decreased risk of mortality and hospitalization from LoRI than being completely sedentary, and incremental risk reduction was observed with increased physical activity.https://www.ahajournals.org/doi/10.1161/JAHA.121.023775cardiovascular diseasedose‐responsephysical activityrespiratory tract infection |
| spellingShingle | Mi‐Hyang Jung Sang‐Wook Yi Sang Joon An Kwan‐Hyun Youn Jee‐Jeon Yi Seongwoo Han Sang‐Hyun Ihm Hae Ok Jung Ho‐Joong Youn Kyu‐Hyung Ryu Association of Physical Activity and Lower Respiratory Tract Infection Outcomes in Patients With Cardiovascular Disease Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease cardiovascular disease dose‐response physical activity respiratory tract infection |
| title | Association of Physical Activity and Lower Respiratory Tract Infection Outcomes in Patients With Cardiovascular Disease |
| title_full | Association of Physical Activity and Lower Respiratory Tract Infection Outcomes in Patients With Cardiovascular Disease |
| title_fullStr | Association of Physical Activity and Lower Respiratory Tract Infection Outcomes in Patients With Cardiovascular Disease |
| title_full_unstemmed | Association of Physical Activity and Lower Respiratory Tract Infection Outcomes in Patients With Cardiovascular Disease |
| title_short | Association of Physical Activity and Lower Respiratory Tract Infection Outcomes in Patients With Cardiovascular Disease |
| title_sort | association of physical activity and lower respiratory tract infection outcomes in patients with cardiovascular disease |
| topic | cardiovascular disease dose‐response physical activity respiratory tract infection |
| url | https://www.ahajournals.org/doi/10.1161/JAHA.121.023775 |
| work_keys_str_mv | AT mihyangjung associationofphysicalactivityandlowerrespiratorytractinfectionoutcomesinpatientswithcardiovasculardisease AT sangwookyi associationofphysicalactivityandlowerrespiratorytractinfectionoutcomesinpatientswithcardiovasculardisease AT sangjoonan associationofphysicalactivityandlowerrespiratorytractinfectionoutcomesinpatientswithcardiovasculardisease AT kwanhyunyoun associationofphysicalactivityandlowerrespiratorytractinfectionoutcomesinpatientswithcardiovasculardisease AT jeejeonyi associationofphysicalactivityandlowerrespiratorytractinfectionoutcomesinpatientswithcardiovasculardisease AT seongwoohan associationofphysicalactivityandlowerrespiratorytractinfectionoutcomesinpatientswithcardiovasculardisease AT sanghyunihm associationofphysicalactivityandlowerrespiratorytractinfectionoutcomesinpatientswithcardiovasculardisease AT haeokjung associationofphysicalactivityandlowerrespiratorytractinfectionoutcomesinpatientswithcardiovasculardisease AT hojoongyoun associationofphysicalactivityandlowerrespiratorytractinfectionoutcomesinpatientswithcardiovasculardisease AT kyuhyungryu associationofphysicalactivityandlowerrespiratorytractinfectionoutcomesinpatientswithcardiovasculardisease |