Evaluation of BAX and BCL-2 Gene Expression Levels and Apoptosis in Resveratrol Affected Human Leukemic Cell Line: CCRF-CEM

Evaluation of BAX and BCL-2 Gene Expression Levels and Apoptosis in Resveratrol Affected Human Leukemic Cell Line: CCRF-CEM

Objectives: Acute lymphoblastic leukemia (ALL) is considered one of the common types of cancers in childhood with an incidence of up to 25%. In addition, drug resistance is a phenomenon which reduces the chances of overcoming cancer. Further, a phytoalexin combination called resveratrol can sensitiz...

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Bibliographic Details
Main Authors: Shiva Pour Vahdani, Taghi Khanzadeh, Fattaneh Karimi, Aylin Jahanban Esfahlan, Somayeh Ghavipanjeh, Amin Ghasemi, Milad Zadi Heydarabad, Hakim Azizi, Akbar Darbin, Arash Khorrami, Ako Azimi
Format: Article
Language:English
Published: Aras Part Medical International Press 2019-04-01
Series:Crescent Journal of Medical and Biological Sciences
Subjects:
leukemia
resveratrol
bcl-2 associated x
bcl-2 gene
apoptosis
Online Access:http://www.cjmb.org/pdf.php?id=228

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