Real clinical practice and contraception for young women with children

The review presents the psychosocial characteristics of young women in todays millennial generation and survey data regarding their hormonal contraceptive requirements. The results of randomized clinical trials and real-life studies of the use of the combined oral contraceptive (COC) Qlaira containi...

Full description

Bibliographic Details
Main Authors: Natalia V. Aganezova, Sergey S. Aganezov
Format: Article
Language:Russian
Published: IP Berlin A.V. 2021-03-01
Series:Гинекология
Subjects:
Online Access:https://gynecology.orscience.ru/2079-5831/article/viewFile/63626/pdf
_version_ 1818906507836653568
author Natalia V. Aganezova
Sergey S. Aganezov
author_facet Natalia V. Aganezova
Sergey S. Aganezov
author_sort Natalia V. Aganezova
collection DOAJ
description The review presents the psychosocial characteristics of young women in todays millennial generation and survey data regarding their hormonal contraceptive requirements. The results of randomized clinical trials and real-life studies of the use of the combined oral contraceptive (COC) Qlaira containing estradiol valerate and dienogest (E2V/DNG) in a dynamic dosing regimen were analyzed, in which the reliability of the contraceptive effect of the drug was identified and confirmed, the restoration of fertility was population level after drug withdrawal, its minimal effect on metabolism and a reduced risk of cardiovascular complications (venous and arterial thrombosis) when using Qlaira COC in comparison with other COCs. The absence of a negative effect of COC E2V/DNG on body weight, sexual function and vaginal microbiocenosis in most women has been proven. The data on satisfactory characteristics of menstrual bleeding (lighter and shorter) in users of Qlaira COC and a decrease in symptoms associated with a hormone-free interval, which often occur when taking other COCs in the 21/7 regimen, are presented. The favorable efficacy and safety profile of COC E2V/DNG in real conditions, the advantages of estrogen bioidentical to the endogenous, in the composition of the drug, the dosage regimen 26/2, the positive effect on the lifestyle, determine the significant satisfaction of young women, including young women with children, and the ability to use the drug for a long time until menopause.
first_indexed 2024-12-19T21:40:20Z
format Article
id doaj.art-d4216e3663d249609119084ebd9aa633
institution Directory Open Access Journal
issn 2079-5696
2079-5831
language Russian
last_indexed 2024-12-19T21:40:20Z
publishDate 2021-03-01
publisher IP Berlin A.V.
record_format Article
series Гинекология
spelling doaj.art-d4216e3663d249609119084ebd9aa6332022-12-21T20:04:41ZrusIP Berlin A.V.Гинекология2079-56962079-58312021-03-01231253210.26442/20795696.2021.1.20062958264Real clinical practice and contraception for young women with childrenNatalia V. Aganezova0https://orcid.org/0000-0002-9676-1570Sergey S. Aganezov1https://orcid.org/0000-0002-3523-9922Mechnikov North-Western State Medical UniversityMechnikov North-Western State Medical UniversityThe review presents the psychosocial characteristics of young women in todays millennial generation and survey data regarding their hormonal contraceptive requirements. The results of randomized clinical trials and real-life studies of the use of the combined oral contraceptive (COC) Qlaira containing estradiol valerate and dienogest (E2V/DNG) in a dynamic dosing regimen were analyzed, in which the reliability of the contraceptive effect of the drug was identified and confirmed, the restoration of fertility was population level after drug withdrawal, its minimal effect on metabolism and a reduced risk of cardiovascular complications (venous and arterial thrombosis) when using Qlaira COC in comparison with other COCs. The absence of a negative effect of COC E2V/DNG on body weight, sexual function and vaginal microbiocenosis in most women has been proven. The data on satisfactory characteristics of menstrual bleeding (lighter and shorter) in users of Qlaira COC and a decrease in symptoms associated with a hormone-free interval, which often occur when taking other COCs in the 21/7 regimen, are presented. The favorable efficacy and safety profile of COC E2V/DNG in real conditions, the advantages of estrogen bioidentical to the endogenous, in the composition of the drug, the dosage regimen 26/2, the positive effect on the lifestyle, determine the significant satisfaction of young women, including young women with children, and the ability to use the drug for a long time until menopause.https://gynecology.orscience.ru/2079-5831/article/viewFile/63626/pdfyoung women with childrenmillennials generationcombined oral contraceptivesestradiol valeratedienogestqlaira
spellingShingle Natalia V. Aganezova
Sergey S. Aganezov
Real clinical practice and contraception for young women with children
Гинекология
young women with children
millennials generation
combined oral contraceptives
estradiol valerate
dienogest
qlaira
title Real clinical practice and contraception for young women with children
title_full Real clinical practice and contraception for young women with children
title_fullStr Real clinical practice and contraception for young women with children
title_full_unstemmed Real clinical practice and contraception for young women with children
title_short Real clinical practice and contraception for young women with children
title_sort real clinical practice and contraception for young women with children
topic young women with children
millennials generation
combined oral contraceptives
estradiol valerate
dienogest
qlaira
url https://gynecology.orscience.ru/2079-5831/article/viewFile/63626/pdf
work_keys_str_mv AT nataliavaganezova realclinicalpracticeandcontraceptionforyoungwomenwithchildren
AT sergeysaganezov realclinicalpracticeandcontraceptionforyoungwomenwithchildren