Preparation and physicochemical characterization of N-succinyl chitosan-coated liposomes for oral delivery of grape seed extract and evaluation of its effect on pulmonary fibrosis induced by bleomycin in rats
Objective(s): This study aimed to develop an oral succinyl chitosan-coated liposomal formulation containing grape seed extract and assess its therapeutic efficacy in rats with bleomycin-induced pulmonary fibrosis. Materials and Methods: N-succinyl chitosan was synthesized, and the liposomal formulat...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Mashhad University of Medical Sciences
2023-10-01
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Series: | Iranian Journal of Basic Medical Sciences |
Subjects: | |
Online Access: | https://ijbms.mums.ac.ir/article_22480_ef27fc3ebcdd6235b01bd7e9aa32fd63.pdf |