Lentiviral Vector Pseudotypes: Precious Tools to Improve Gene Modification of Hematopoietic Cells for Research and Gene Therapy

Lentiviral Vector Pseudotypes: Precious Tools to Improve Gene Modification of Hematopoietic Cells for Research and Gene Therapy

Viruses have been repurposed into tools for gene delivery by transforming them into viral vectors. The most frequently used vectors are lentiviral vectors (LVs), derived from the human immune deficiency virus allowing efficient gene transfer in mammalian cells. They represent one of the safest and m...

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Bibliographic Details
Main Authors: Alejandra Gutierrez-Guerrero, François-Loïc Cosset, Els Verhoeyen
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Viruses
Subjects:
lentiviral vector
gene therapy
T cell
B cell
HSC
CRISPR/CAS9
Online Access:https://www.mdpi.com/1999-4915/12/9/1016

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