Structural insights into the activity and regulation of human Josephin-2
The MJD family of human deubiquitinating enzymes contains four members: Ataxin-3, the ataxin-3-like protein (AT3L), Josephin-1, and Josephin-2. All share a conserved catalytic unit known as the Josephin domain. Ataxin-3 and AT3L also contain extensive regulatory regions that modulate their functions...
Main Authors: | Kimberly C. Grasty, Stephen D. Weeks, Patrick J. Loll |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2019-07-01
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Series: | Journal of Structural Biology: X |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2590152419300091 |
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