Primary adherence to antidepressant prescriptions in primary health care: a population-based study in Sweden

Background Medical adherence is important in the treatment of depression. Primary medical adherence, i.e. patients collecting their newly prescribed medications from pharmacies, is very different depending on the drug prescribed Objective To assess the rate of primary medical adherence in patients p...

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Main Authors: Carl Freccero, Kristina Sundquist, Jan Sundquist, Jianguang Ji
Format: Article
Language:English
Published: Taylor & Francis Group 2016-01-01
Series:Scandinavian Journal of Primary Health Care
Subjects:
Online Access:http://dx.doi.org/10.3109/02813432.2015.1132884
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author Carl Freccero
Kristina Sundquist
Jan Sundquist
Jianguang Ji
author_facet Carl Freccero
Kristina Sundquist
Jan Sundquist
Jianguang Ji
author_sort Carl Freccero
collection DOAJ
description Background Medical adherence is important in the treatment of depression. Primary medical adherence, i.e. patients collecting their newly prescribed medications from pharmacies, is very different depending on the drug prescribed Objective To assess the rate of primary medical adherence in patients prescribed antidepressants and to identify characteristics that make patients less likely to pick up prescriptions. Methods An observational study was performed using primary health care data from Sweden on patients who were prescribed antidepressants. Univariate and multivariate logistic regression was used to determine differences in pick-up rate according to patient characteristics. Main outcome Pick-up rate, defined as collection of a prescription within 30 days. Results A total of 11 624 patients received an antidepressant prescription during the study period, and the overall pick-up rate was 85.1%. The pick-up rate differed according to country of birth: individuals born in the Middle East and other countries outside Europe had lower primary medical adherence than Swedes, with adjusted odds ratios (ORs) of 0.58 and 0.67, respectively. Patients at ages 64–79 years had a higher pick-up rate compared with those aged 25–44 years (OR 1.71). Divorced patients had a lower rate compared with married patients (OR 0.80). Conclusion Immigrants from the Middle East and other countries outside Europe and younger and divorced patients had lower primary medical adherence, which calls for clinical attention and preventive measures.Key points Primary medical adherence is important in the treatment of depression. Are patient characteristics associated with primary medical adherence? The overall primary medical adherence rate was 85%. The rate differed by country of birth, age at diagnosis of depression, and marital status. Clinical attention is needed in patients who do not pick up their antidepressants.
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spelling doaj.art-d42643c8596840aeac674327a55b5f632022-12-21T19:40:23ZengTaylor & Francis GroupScandinavian Journal of Primary Health Care0281-34321502-77242016-01-01341838810.3109/02813432.2015.11328841132884Primary adherence to antidepressant prescriptions in primary health care: a population-based study in SwedenCarl Freccero0Kristina Sundquist1Jan Sundquist2Jianguang Ji3Lund University/Region SkåneLund University/Region SkåneLund University/Region SkåneLund University/Region SkåneBackground Medical adherence is important in the treatment of depression. Primary medical adherence, i.e. patients collecting their newly prescribed medications from pharmacies, is very different depending on the drug prescribed Objective To assess the rate of primary medical adherence in patients prescribed antidepressants and to identify characteristics that make patients less likely to pick up prescriptions. Methods An observational study was performed using primary health care data from Sweden on patients who were prescribed antidepressants. Univariate and multivariate logistic regression was used to determine differences in pick-up rate according to patient characteristics. Main outcome Pick-up rate, defined as collection of a prescription within 30 days. Results A total of 11 624 patients received an antidepressant prescription during the study period, and the overall pick-up rate was 85.1%. The pick-up rate differed according to country of birth: individuals born in the Middle East and other countries outside Europe had lower primary medical adherence than Swedes, with adjusted odds ratios (ORs) of 0.58 and 0.67, respectively. Patients at ages 64–79 years had a higher pick-up rate compared with those aged 25–44 years (OR 1.71). Divorced patients had a lower rate compared with married patients (OR 0.80). Conclusion Immigrants from the Middle East and other countries outside Europe and younger and divorced patients had lower primary medical adherence, which calls for clinical attention and preventive measures.Key points Primary medical adherence is important in the treatment of depression. Are patient characteristics associated with primary medical adherence? The overall primary medical adherence rate was 85%. The rate differed by country of birth, age at diagnosis of depression, and marital status. Clinical attention is needed in patients who do not pick up their antidepressants.http://dx.doi.org/10.3109/02813432.2015.1132884Antidepressant medicationgeneral practicemedical adherencepatient characteristicspick-up rateprimary medical adherenceSweden
spellingShingle Carl Freccero
Kristina Sundquist
Jan Sundquist
Jianguang Ji
Primary adherence to antidepressant prescriptions in primary health care: a population-based study in Sweden
Scandinavian Journal of Primary Health Care
Antidepressant medication
general practice
medical adherence
patient characteristics
pick-up rate
primary medical adherence
Sweden
title Primary adherence to antidepressant prescriptions in primary health care: a population-based study in Sweden
title_full Primary adherence to antidepressant prescriptions in primary health care: a population-based study in Sweden
title_fullStr Primary adherence to antidepressant prescriptions in primary health care: a population-based study in Sweden
title_full_unstemmed Primary adherence to antidepressant prescriptions in primary health care: a population-based study in Sweden
title_short Primary adherence to antidepressant prescriptions in primary health care: a population-based study in Sweden
title_sort primary adherence to antidepressant prescriptions in primary health care a population based study in sweden
topic Antidepressant medication
general practice
medical adherence
patient characteristics
pick-up rate
primary medical adherence
Sweden
url http://dx.doi.org/10.3109/02813432.2015.1132884
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