BioCloneBot: A versatile, low-cost, and open-source automated liquid handler
Liquid handler systems can provide significant benefits to researchers by automating laboratory work, however, their unaffordable price provides a steep barrier to entry. Therefore, we provide the BioCloneBot, a versatile, low-cost, and open-source automated liquid handler. This system can be easily...
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Format: | Article |
Language: | English |
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Elsevier
2024-06-01
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Series: | HardwareX |
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Online Access: | http://www.sciencedirect.com/science/article/pii/S2468067224000105 |
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author | Ke’Koa CDH Wells Nawwaf Kharma Brandon B. Jaunky Kaiyu Nie Gabriel Aguiar-Tawil Daniel Berry |
author_facet | Ke’Koa CDH Wells Nawwaf Kharma Brandon B. Jaunky Kaiyu Nie Gabriel Aguiar-Tawil Daniel Berry |
author_sort | Ke’Koa CDH Wells |
collection | DOAJ |
description | Liquid handler systems can provide significant benefits to researchers by automating laboratory work, however, their unaffordable price provides a steep barrier to entry. Therefore, we provide the BioCloneBot, a versatile, low-cost, and open-source automated liquid handler. This system can be easily built with 3D-printed parts and readily available commercial components. The BioCloneBot is highly adaptive to user needs and facilitates various liquid handling tasks in research and diagnostics. Its user-friendly interface and programmable nature make it suitable for a wide range of applications, from small-scale experiments to larger laboratory setups. By utilizing BioCloneBot, researchers and scientists can streamline their liquid handling processes without the financial constraints posed by traditional systems. In this paper, we detail the design, construction, and validation of BioCloneBot, showcasing its precise control, accuracy, and repeatability in various liquid handling tasks. The open-source nature of the system encourages collaboration and customization, enabling researchers to contribute and adapt the technology to specific experimental requirements. |
first_indexed | 2024-04-24T23:48:03Z |
format | Article |
id | doaj.art-d427e1715f404216aae32a0657ef7712 |
institution | Directory Open Access Journal |
issn | 2468-0672 |
language | English |
last_indexed | 2025-03-21T17:33:31Z |
publishDate | 2024-06-01 |
publisher | Elsevier |
record_format | Article |
series | HardwareX |
spelling | doaj.art-d427e1715f404216aae32a0657ef77122024-06-13T04:45:23ZengElsevierHardwareX2468-06722024-06-0118e00516BioCloneBot: A versatile, low-cost, and open-source automated liquid handlerKe’Koa CDH Wells0Nawwaf Kharma1Brandon B. Jaunky2Kaiyu Nie3Gabriel Aguiar-Tawil4Daniel Berry5Department of Electrical and Computer Engineering, Concordia University, Montréal, Québec, CanadaDepartment of Electrical and Computer Engineering, Concordia University, Montréal, Québec, Canada; Department of Biology, Concordia University, Montréal, Québec, Canada; Corresponding author at: Department of Electrical and Computer Engineering, Concordia University, Montréal, Québec, Canada.Department of Biology, Concordia University, Montréal, Québec, CanadaDepartment of Electrical and Computer Engineering, Concordia University, Montréal, Québec, CanadaDepartment of Biology, Concordia University, Montréal, Québec, CanadaDepartment of Mechanical, Industrial and Aerospace Engineering, Concordia University, Montréal, Québec, CanadaLiquid handler systems can provide significant benefits to researchers by automating laboratory work, however, their unaffordable price provides a steep barrier to entry. Therefore, we provide the BioCloneBot, a versatile, low-cost, and open-source automated liquid handler. This system can be easily built with 3D-printed parts and readily available commercial components. The BioCloneBot is highly adaptive to user needs and facilitates various liquid handling tasks in research and diagnostics. Its user-friendly interface and programmable nature make it suitable for a wide range of applications, from small-scale experiments to larger laboratory setups. By utilizing BioCloneBot, researchers and scientists can streamline their liquid handling processes without the financial constraints posed by traditional systems. In this paper, we detail the design, construction, and validation of BioCloneBot, showcasing its precise control, accuracy, and repeatability in various liquid handling tasks. The open-source nature of the system encourages collaboration and customization, enabling researchers to contribute and adapt the technology to specific experimental requirements.http://www.sciencedirect.com/science/article/pii/S2468067224000105Open-sourceLiquid handlerSynthetic biologyDNA cloning3D printing |
spellingShingle | Ke’Koa CDH Wells Nawwaf Kharma Brandon B. Jaunky Kaiyu Nie Gabriel Aguiar-Tawil Daniel Berry BioCloneBot: A versatile, low-cost, and open-source automated liquid handler HardwareX Open-source Liquid handler Synthetic biology DNA cloning 3D printing |
title | BioCloneBot: A versatile, low-cost, and open-source automated liquid handler |
title_full | BioCloneBot: A versatile, low-cost, and open-source automated liquid handler |
title_fullStr | BioCloneBot: A versatile, low-cost, and open-source automated liquid handler |
title_full_unstemmed | BioCloneBot: A versatile, low-cost, and open-source automated liquid handler |
title_short | BioCloneBot: A versatile, low-cost, and open-source automated liquid handler |
title_sort | bioclonebot a versatile low cost and open source automated liquid handler |
topic | Open-source Liquid handler Synthetic biology DNA cloning 3D printing |
url | http://www.sciencedirect.com/science/article/pii/S2468067224000105 |
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