Whole blood as an alternative to peripheral blood mononuclear cell for detection of total HIV-1 DNA

Whole blood as an alternative to peripheral blood mononuclear cell for detection of total HIV-1 DNA

Abstract Background A more time saving, convenient, reproducible, and scalable method is needed to assess total HIV-1 DNA levels. Methods Frozen whole blood and peripheral blood mononuclear cell (PBMC) samples both 200 μl at the same point were used to detect total HIV-1 DNA. Automatic extraction of...

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Bibliographic Details
Main Authors: Ling Lin, Yong-Song Yue, Ni-Dan Wang, Lei-Yan Wei, Yang Han, Xiao-Jing Song, Zhi-Feng Qiu, Wei Cao, Tai-Sheng Li
Format: Article
Language:English
Published: BMC 2020-12-01
Series:BMC Infectious Diseases
Subjects:
AIDS
HIV-1 DNA
Peripheral blood mononuclear cell
Reservoir
Whole blood
Online Access:https://doi.org/10.1186/s12879-020-05675-3

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