Plasmodium Topoisomerase VIB and Spo11 Constitute Functional Type IIB Topoisomerase in Malaria Parasite: Its Possible Role in Mitochondrial DNA Segregation

Plasmodium Topoisomerase VIB and Spo11 Constitute Functional Type IIB Topoisomerase in Malaria Parasite: Its Possible Role in Mitochondrial DNA Segregation

ABSTRACT The human malaria parasite undergoes a noncanonical cell division, namely, endoreduplication, where several rounds of nuclear, mitochondrial, and apicoplast replication occur without cytoplasmic division. Despite its importance in Plasmodium biology, the topoisomerases essential for decaten...

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Bibliographic Details
Main Authors: Priyanka Singh, Wahida Tabassum, Nupur Fangaria, Sandeep Dey, Siladitya Padhi, Mrinal K. Bhattacharyya, Kota Arun Kumar, Arijit Roy, Sunanda Bhattacharyya
Format: Article
Language:English
Published: American Society for Microbiology 2023-06-01
Series:Microbiology Spectrum
Subjects:
Plasmodium mitochondria
Plasmodium topoisomerase VI
apicomplexan topoisomerase
Online Access:https://journals.asm.org/doi/10.1128/spectrum.04980-22

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