Multidrug-resistant (MDR) Staphylococcus aureus in a Maracaibo’s hospital, Venezuela
Oxacillin-resistant Staphylococcus aureus (ORSA) has remained a major cause of nosocomial infections worldwide. The antibiotic resistance of isolations was determined and we classify them in multidrug-resistant, extensively drug-resistant or pandrug-resistant. The biological samples of patients from...
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| Format: | Article |
| Language: | English |
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Universidad del Zulia,Facultad de Medicina,Departamento de Enfermedades Infecciosas y Tropicales
2016-08-01
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| Series: | Kasmera |
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| Online Access: | https://produccioncientificaluz.org/index.php/kasmera/article/view/21302 |
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| author | Liliana Gómez-Gamboa Daniela Núñez-Chacín Armindo Perozo-Mena José Bermúdez-González Milagros Marín |
| author_facet | Liliana Gómez-Gamboa Daniela Núñez-Chacín Armindo Perozo-Mena José Bermúdez-González Milagros Marín |
| author_sort | Liliana Gómez-Gamboa |
| collection | DOAJ |
| description | Oxacillin-resistant Staphylococcus aureus (ORSA) has remained a major cause of nosocomial infections worldwide. The antibiotic resistance of isolations was determined and we classify them in multidrug-resistant, extensively drug-resistant or pandrug-resistant. The biological samples of patients from a Maracaibo’s Hospital, during September 2013 to February 2014, were processed according to conventional techniques of bacteriology. Antibiotic resistance was determined by disk diffusion method in agar and the mecA gene was detected by polymerase chain reaction. It was observed a low prevalence of nosocomial ORSA (13.86%). The higher antibiotic resistance was observed against erythromycin (66.07%) and a resistance lower than 25% to aminoglycosides, fluoroquinolones, tetracycline and clindamycin. The isolates showed a very low resistance to trimethoprim/sulfamethoxazole and all isolates were susceptible to rifampicin, linezolid, vancomycin and teicoplanin.The majority of isolates had a MSB phenotype (33.93%), with erythromycin resistance and susceptibility to clindamycin. The ORSA isolates in this study had 25 different antibiotypes and the majority of them were multidrug-resistant (55.36%). There was not both extensively drugresistant and pandrug-resistant isolates and the presence of the mecA gene was demonstrated in all isolates of ORSA. |
| first_indexed | 2024-03-12T06:33:28Z |
| format | Article |
| id | doaj.art-d42ea203e81f4fbdba22ba1a418c2f34 |
| institution | Directory Open Access Journal |
| issn | 0075-5222 2477-9628 |
| language | English |
| last_indexed | 2024-03-12T06:33:28Z |
| publishDate | 2016-08-01 |
| publisher | Universidad del Zulia,Facultad de Medicina,Departamento de Enfermedades Infecciosas y Tropicales |
| record_format | Article |
| series | Kasmera |
| spelling | doaj.art-d42ea203e81f4fbdba22ba1a418c2f342023-09-03T01:29:46ZengUniversidad del Zulia,Facultad de Medicina,Departamento de Enfermedades Infecciosas y TropicalesKasmera0075-52222477-96282016-08-01441536521098Multidrug-resistant (MDR) Staphylococcus aureus in a Maracaibo’s hospital, VenezuelaLiliana Gómez-Gamboa0Daniela Núñez-Chacín1Armindo Perozo-Mena2José Bermúdez-González3Milagros Marín4Cátedra de Microbiología, Escuela de Medicina, Universidad del ZuliaPrograma de Maestría en Diagnóstico Bacteriológico, Universidad del ZuliaPráctica Profesional de Bacteriología, Escuela de Bioanálisis, Universidad del ZuliaBios Venezuela C.A.Programa de Maestría en Diagnóstico Bacteriológico, Universidad del ZuliaOxacillin-resistant Staphylococcus aureus (ORSA) has remained a major cause of nosocomial infections worldwide. The antibiotic resistance of isolations was determined and we classify them in multidrug-resistant, extensively drug-resistant or pandrug-resistant. The biological samples of patients from a Maracaibo’s Hospital, during September 2013 to February 2014, were processed according to conventional techniques of bacteriology. Antibiotic resistance was determined by disk diffusion method in agar and the mecA gene was detected by polymerase chain reaction. It was observed a low prevalence of nosocomial ORSA (13.86%). The higher antibiotic resistance was observed against erythromycin (66.07%) and a resistance lower than 25% to aminoglycosides, fluoroquinolones, tetracycline and clindamycin. The isolates showed a very low resistance to trimethoprim/sulfamethoxazole and all isolates were susceptible to rifampicin, linezolid, vancomycin and teicoplanin.The majority of isolates had a MSB phenotype (33.93%), with erythromycin resistance and susceptibility to clindamycin. The ORSA isolates in this study had 25 different antibiotypes and the majority of them were multidrug-resistant (55.36%). There was not both extensively drugresistant and pandrug-resistant isolates and the presence of the mecA gene was demonstrated in all isolates of ORSA.https://produccioncientificaluz.org/index.php/kasmera/article/view/21302Staphylococcus aureusresistencia a oxacilinamultidrogo-resistenciagen mecAantibiotipos |
| spellingShingle | Liliana Gómez-Gamboa Daniela Núñez-Chacín Armindo Perozo-Mena José Bermúdez-González Milagros Marín Multidrug-resistant (MDR) Staphylococcus aureus in a Maracaibo’s hospital, Venezuela Kasmera Staphylococcus aureus resistencia a oxacilina multidrogo-resistencia gen mecA antibiotipos |
| title | Multidrug-resistant (MDR) Staphylococcus aureus in a Maracaibo’s hospital, Venezuela |
| title_full | Multidrug-resistant (MDR) Staphylococcus aureus in a Maracaibo’s hospital, Venezuela |
| title_fullStr | Multidrug-resistant (MDR) Staphylococcus aureus in a Maracaibo’s hospital, Venezuela |
| title_full_unstemmed | Multidrug-resistant (MDR) Staphylococcus aureus in a Maracaibo’s hospital, Venezuela |
| title_short | Multidrug-resistant (MDR) Staphylococcus aureus in a Maracaibo’s hospital, Venezuela |
| title_sort | multidrug resistant mdr staphylococcus aureus in a maracaibo s hospital venezuela |
| topic | Staphylococcus aureus resistencia a oxacilina multidrogo-resistencia gen mecA antibiotipos |
| url | https://produccioncientificaluz.org/index.php/kasmera/article/view/21302 |
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