Analysis of N7-(2-carbamoyl-2-hydroxyethyl)guanine in dried blood spot after food exposure by Ultra High Performance Liquid Chromatography–Tandem Mass Spectrometry

Analysis of N7-(2-carbamoyl-2-hydroxyethyl)guanine in dried blood spot after food exposure by Ultra High Performance Liquid Chromatography–Tandem Mass Spectrometry

Abstract N7-(2-carbamoyl-2-hydroxyethyl)guanine (N7-CAG) is a DNA adduct formed by glycidamide, which is the metabolite of acrylamide. Acrylamide can be found in foods containing reducing sugars and asparagine that are heated at high temperatures. Analysis of N7-CAG was performed in Dried Blood Spot...

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Bibliographic Details
Main Authors: Yahdiana Harahap, Winning Bekti Safitri, Sunarsih Sunarsih
Format: Article
Language:English
Published: BMC 2022-11-01
Series:BMC Chemistry
Subjects:
N7-(2-carbamoyl-2-hydroxyethyl)guanine
Acrylamide
Dried blood spot
UHPLC-MS/MS
Online Access:https://doi.org/10.1186/s13065-022-00875-1

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