Implications of GABAergic neurotransmission in Alzheimer’s disease

Implications of GABAergic neurotransmission in Alzheimer’s disease

Alzheimer’s disease (AD) is characterized pathologically by the deposition of -amyloid peptides (A) and the accumulation of neurofibrillary tangles (NFTs) composed of hyper-phosphorylated tau. Regardless of the pathological hallmarks, synaptic dysfunction is widely accepted as a causal event in AD...

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Bibliographic Details
Main Authors:	Yanfang eLi, Hao eSun, Zhicai eChen, Huaxi eXu, Guojun eBu, Hui eZheng
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2016-02-01
Series:	Frontiers in Aging Neuroscience
Subjects:	Amyloid beta-Peptides Apolipoproteins E tau Proteins gabaergic neurotransmission neuronal inhibition
Online Access:	http://journal.frontiersin.org/Journal/10.3389/fnagi.2016.00031/full

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