Factors influencing relapse in patients with schizophrenia
Introduction: Relapse is a major factor for disability and poor quality of life in patients with schizophrenia. Several factors contribute to the relapse of symptoms in schizophrenia. Studying the modifiable factors helps in planning relapse prevention strategies. Aims: The study aimed to assess the...
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| Format: | Article |
| Language: | English |
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Indian Psychiatric Society (Kerala State Branch
2023-01-01
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| Series: | Kerala Journal of Psychiatry |
| Subjects: | |
| Online Access: | https://kjponline.com/index.php/kjp/article/view/294 |
| _version_ | 1797659209134768128 |
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| author | P Nabeel T K Saleem A M Ashfaq-U-Rahman |
| author_facet | P Nabeel T K Saleem A M Ashfaq-U-Rahman |
| author_sort | P Nabeel |
| collection | DOAJ |
| description | Introduction: Relapse is a major factor for disability and poor quality of life in patients with schizophrenia. Several factors contribute to the relapse of symptoms in schizophrenia. Studying the modifiable factors helps in planning relapse prevention strategies. Aims: The study aimed to assess the factors influencing relapse among patients with schizophrenia. The study focused on selected modifiable factors such as stressful life events, perceived stress, expressed emotion, drug compliance and perceived stigma. Methods: A comparative design was used for this study. Tools used for data collection included a semi-structured interview schedule, Life Change Index Scale, Perceived Stress Scale, Medication Adherence Rating Scale, Family Emotional Involvement and Criticism Scale and STIG-9 questionnaire. Purposive sampling technique was used. The sample consisted of two groups of patients with schizophrenia, 50 patients in relapse and another group of 50 patients in remission. Results: The two groups were comparable in terms of socio-demographic and clinical variables, except for history of substance use. The mean (Standard deviation) scores of stressful life events were higher for the relapse group [159.82 (53.87)] compared to controls [114.42 (30.98), p < 0.001]; so also, for perceived stress [12.40 (3.54) and 7.26 (2.93), p < 0.0001)]; expressed emotion [27.36 (6.19) and 17.24 (5.64), p < 0.001)]; poor drug compliance [3.78 (1.94) and 7.60 (1.67), p < 0.001], perceived stigma [14.46 (3.53) and 12.38 (3.28), p = 0.003]. Conclusion: Knowledge of factors that contribute to relapse in schizophrenia will help mental health service providers to improve the standards of care. Interventions in schizophrenia should specifically target relapse prevention and improved quality of life. |
| first_indexed | 2024-03-11T18:11:35Z |
| format | Article |
| id | doaj.art-d439cfb736b5436dbf8854248b6ad7f8 |
| institution | Directory Open Access Journal |
| issn | 0377-0699 2395-1486 |
| language | English |
| last_indexed | 2024-03-11T18:11:35Z |
| publishDate | 2023-01-01 |
| publisher | Indian Psychiatric Society (Kerala State Branch |
| record_format | Article |
| series | Kerala Journal of Psychiatry |
| spelling | doaj.art-d439cfb736b5436dbf8854248b6ad7f82023-10-16T13:53:19ZengIndian Psychiatric Society (Kerala State BranchKerala Journal of Psychiatry0377-06992395-14862023-01-0135213113810.30834/KJP.35.2.2023.294255Factors influencing relapse in patients with schizophreniaP Nabeel0T K Saleem1A M Ashfaq-U-Rahman2Assistant Professor, Government College of Nursing, Kozhikode, Kerala, IndiaAssistant Professor, Government College of Nursing, Kozhikode, Kerala, IndiaAssistant Professor, Department of Psychiatry, Medical College, Kozhikode, KeralaIntroduction: Relapse is a major factor for disability and poor quality of life in patients with schizophrenia. Several factors contribute to the relapse of symptoms in schizophrenia. Studying the modifiable factors helps in planning relapse prevention strategies. Aims: The study aimed to assess the factors influencing relapse among patients with schizophrenia. The study focused on selected modifiable factors such as stressful life events, perceived stress, expressed emotion, drug compliance and perceived stigma. Methods: A comparative design was used for this study. Tools used for data collection included a semi-structured interview schedule, Life Change Index Scale, Perceived Stress Scale, Medication Adherence Rating Scale, Family Emotional Involvement and Criticism Scale and STIG-9 questionnaire. Purposive sampling technique was used. The sample consisted of two groups of patients with schizophrenia, 50 patients in relapse and another group of 50 patients in remission. Results: The two groups were comparable in terms of socio-demographic and clinical variables, except for history of substance use. The mean (Standard deviation) scores of stressful life events were higher for the relapse group [159.82 (53.87)] compared to controls [114.42 (30.98), p < 0.001]; so also, for perceived stress [12.40 (3.54) and 7.26 (2.93), p < 0.0001)]; expressed emotion [27.36 (6.19) and 17.24 (5.64), p < 0.001)]; poor drug compliance [3.78 (1.94) and 7.60 (1.67), p < 0.001], perceived stigma [14.46 (3.53) and 12.38 (3.28), p = 0.003]. Conclusion: Knowledge of factors that contribute to relapse in schizophrenia will help mental health service providers to improve the standards of care. Interventions in schizophrenia should specifically target relapse prevention and improved quality of life.https://kjponline.com/index.php/kjp/article/view/294relapse, schizophrenia, risk factors |
| spellingShingle | P Nabeel T K Saleem A M Ashfaq-U-Rahman Factors influencing relapse in patients with schizophrenia Kerala Journal of Psychiatry relapse, schizophrenia, risk factors |
| title | Factors influencing relapse in patients with schizophrenia |
| title_full | Factors influencing relapse in patients with schizophrenia |
| title_fullStr | Factors influencing relapse in patients with schizophrenia |
| title_full_unstemmed | Factors influencing relapse in patients with schizophrenia |
| title_short | Factors influencing relapse in patients with schizophrenia |
| title_sort | factors influencing relapse in patients with schizophrenia |
| topic | relapse, schizophrenia, risk factors |
| url | https://kjponline.com/index.php/kjp/article/view/294 |
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