Prevention of Ovarian Hyperstimulation Syndrome in Patients with Polycystic Ovarian Syndrome By Using Midfollicular FSH/LH Ratio and Counting Number(S) of Ovarian Follicles
The objective of this study was to examine the correlation between both midfollicular FSH/LH ratio and number(s) of follicles with ovarian hyperstimulation syndrome (OHSS) in patients with polycystic ovarian syndrome (PCOS). This was carried out in IVF unit at Mirza Kouchak Khan Hospital. To induce...
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| Format: | Article |
| Language: | fas |
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Tehran University of Medical Sciences
2001-06-01
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| Series: | Tehran University Medical Journal |
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| Online Access: | http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/5591.pdf&manuscript_id=5591 |
| _version_ | 1811255680722534400 |
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| author | F Akbari Asbagh |
| author_facet | F Akbari Asbagh |
| author_sort | F Akbari Asbagh |
| collection | DOAJ |
| description | The objective of this study was to examine the correlation between both midfollicular FSH/LH ratio and number(s) of follicles with ovarian hyperstimulation syndrome (OHSS) in patients with polycystic ovarian syndrome (PCOS). This was carried out in IVF unit at Mirza Kouchak Khan Hospital. To induce ovulation, PCOS patients were stimulated with gonadotropines. Fifty four PCOS patients with normal basal level of FSH, LH were studied prospectively. 22 patients did not receive HCG and stimulation cycle was canceled due to OHSS. 32 patients received HCG and stimulation cycle was completed. In all patients mid-follicular (day 8 of stimulation protocol) serum FSH/LH ratio was measured. On the same day number of ovarian follicles were also counted using vaginal sonography. In canceled cycles, LH on day 8 was shown to be low along with increased number of follicles. The risk of cycle cancelation raised twice with one increment of FSH/LH ratio. Also, with increase of one follicle the risk of cycle cancellation increased 1.3 times. To induce ovulation by gonadotropine stimulation in PCOS patients, the dose should be carefully monitored. Measuring FSH/LH ratio and number of follicles on day 8 of stimulation protocol are reliable guides in order to predict those patients prone to develop OHSS. |
| first_indexed | 2024-04-12T17:28:34Z |
| format | Article |
| id | doaj.art-d43c5d2ad9ed476c83a385b0a3f436c8 |
| institution | Directory Open Access Journal |
| issn | 1683-1764 1735-7322 |
| language | fas |
| last_indexed | 2024-04-12T17:28:34Z |
| publishDate | 2001-06-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Tehran University Medical Journal |
| spelling | doaj.art-d43c5d2ad9ed476c83a385b0a3f436c82022-12-22T03:23:12ZfasTehran University of Medical SciencesTehran University Medical Journal1683-17641735-73222001-06-015915963Prevention of Ovarian Hyperstimulation Syndrome in Patients with Polycystic Ovarian Syndrome By Using Midfollicular FSH/LH Ratio and Counting Number(S) of Ovarian FolliclesF Akbari AsbaghThe objective of this study was to examine the correlation between both midfollicular FSH/LH ratio and number(s) of follicles with ovarian hyperstimulation syndrome (OHSS) in patients with polycystic ovarian syndrome (PCOS). This was carried out in IVF unit at Mirza Kouchak Khan Hospital. To induce ovulation, PCOS patients were stimulated with gonadotropines. Fifty four PCOS patients with normal basal level of FSH, LH were studied prospectively. 22 patients did not receive HCG and stimulation cycle was canceled due to OHSS. 32 patients received HCG and stimulation cycle was completed. In all patients mid-follicular (day 8 of stimulation protocol) serum FSH/LH ratio was measured. On the same day number of ovarian follicles were also counted using vaginal sonography. In canceled cycles, LH on day 8 was shown to be low along with increased number of follicles. The risk of cycle cancelation raised twice with one increment of FSH/LH ratio. Also, with increase of one follicle the risk of cycle cancellation increased 1.3 times. To induce ovulation by gonadotropine stimulation in PCOS patients, the dose should be carefully monitored. Measuring FSH/LH ratio and number of follicles on day 8 of stimulation protocol are reliable guides in order to predict those patients prone to develop OHSS.http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/5591.pdf&manuscript_id=5591Ovarian Hyperstimulation SyndromPolycystic Ovarian SyndromOvarian FolliclesFSH/RH Ratio |
| spellingShingle | F Akbari Asbagh Prevention of Ovarian Hyperstimulation Syndrome in Patients with Polycystic Ovarian Syndrome By Using Midfollicular FSH/LH Ratio and Counting Number(S) of Ovarian Follicles Tehran University Medical Journal Ovarian Hyperstimulation Syndrom Polycystic Ovarian Syndrom Ovarian Follicles FSH/RH Ratio |
| title | Prevention of Ovarian Hyperstimulation Syndrome in Patients with Polycystic Ovarian Syndrome By Using Midfollicular FSH/LH Ratio and Counting Number(S) of Ovarian Follicles |
| title_full | Prevention of Ovarian Hyperstimulation Syndrome in Patients with Polycystic Ovarian Syndrome By Using Midfollicular FSH/LH Ratio and Counting Number(S) of Ovarian Follicles |
| title_fullStr | Prevention of Ovarian Hyperstimulation Syndrome in Patients with Polycystic Ovarian Syndrome By Using Midfollicular FSH/LH Ratio and Counting Number(S) of Ovarian Follicles |
| title_full_unstemmed | Prevention of Ovarian Hyperstimulation Syndrome in Patients with Polycystic Ovarian Syndrome By Using Midfollicular FSH/LH Ratio and Counting Number(S) of Ovarian Follicles |
| title_short | Prevention of Ovarian Hyperstimulation Syndrome in Patients with Polycystic Ovarian Syndrome By Using Midfollicular FSH/LH Ratio and Counting Number(S) of Ovarian Follicles |
| title_sort | prevention of ovarian hyperstimulation syndrome in patients with polycystic ovarian syndrome by using midfollicular fsh lh ratio and counting number s of ovarian follicles |
| topic | Ovarian Hyperstimulation Syndrom Polycystic Ovarian Syndrom Ovarian Follicles FSH/RH Ratio |
| url | http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/5591.pdf&manuscript_id=5591 |
| work_keys_str_mv | AT fakbariasbagh preventionofovarianhyperstimulationsyndromeinpatientswithpolycysticovariansyndromebyusingmidfollicularfshlhratioandcountingnumbersofovarianfollicles |